about
Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasisTitration-Based Screening for Evaluation of Natural Product Extracts: Identification of an Aspulvinone Family of Luciferase InhibitorsThe Art of Filling Protein Pockets Efficiently with Octahedral Metal ComplexesTheonellasterone, a steroidal metabolite isolated from a Theonella sponge, protects peroxiredoxin-1 from oxidative stress reactionsTarget identification by image analysisModern natural products drug discovery and its relevance to biodiversity conservationNeuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin ASimultaneous structure-activity studies and arming of natural products by C-H amination reveal cellular targets of eupalmerin acetate.Privileged diazepine compounds and their emergence as bromodomain inhibitors.Chemo- and site-selective derivatizations of natural products enabling biological studies.Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Chemical assay-guided natural product isolation via solid-supported chemodosimetric fluorescent probe.Highlights of marine invertebrate-derived biosynthetic products: their biomedical potential and possible production by microbial associantsParasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent.Translating Nature's Library: The Bryostatins and Function-Oriented SynthesisSynthesis and cytotoxicity studies of novel triazolo-benzoxazepine as new anticancer agents.Biological targets and mechanisms of action of natural products from marine cyanobacteria.Tagging polyketides/non-ribosomal peptides with a clickable functionality and applications.Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery.Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product ExtractsA prevalent peptide-binding domain guides ribosomal natural product biosynthesis.Target identification for biologically active small molecules using chemical biology approaches.Identification of Limonol Derivatives as Heat Shock Protein 90 (Hsp90) Inhibitors through a Multidisciplinary Approach.Highly Stereoselective Synthesis of a Compound Collection Based on the Bicyclic Scaffolds of Natural Products.Aplysqualenol A binds to the light chain of dynein type 1 (DYNLL1).Lipoprotein activators stimulate Escherichia coli penicillin-binding proteins by different mechanisms.From conventional to unusual enzyme inhibitor scaffolds: the quest for target specificity.Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids.Nano-enabled biomarker discovery and detection.Survey of marine natural product structure revisions: a synergy of spectroscopy and chemical synthesis.History, biology and chemistry of Mycobacterium ulcerans infections (Buruli ulcer disease).Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents.Discovery of novel drug targets and their functions using phenotypic screening of natural products.Synthesis and mode of action of oligomeric sesquiterpene lactones.Engineering microbial hosts for production of bacterial natural productsModern advances in heterocyclic chemistry in drug discovery.Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds.Siloxyl ether functionalized resins for chemoselective enrichment of carboxylic acids.Targeting Reactive Carbonyls for Identifying Natural Products and Their Biosynthetic Origins.Diazo reagents with small steric footprints for simultaneous arming/SAR studies of alcohol-containing natural products via O-H insertion.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Natural products as chemical probes
@ast
Natural products as chemical probes
@en
type
label
Natural products as chemical probes
@ast
Natural products as chemical probes
@en
prefLabel
Natural products as chemical probes
@ast
Natural products as chemical probes
@en
P2860
P356
P1433
P1476
Natural products as chemical probes
@en
P2093
Erin E Carlson
P2860
P304
P356
10.1021/CB100105C
P577
2010-07-01T00:00:00Z