Visualizing lowly-populated regions of the free energy landscape of macromolecular complexes by paramagnetic relaxation enhancement
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The ensemble nature of allosteryPrinciples of allosteric interactions in cell signalingTowards physiological complexity with in vitro single-molecule biophysicsDynamic regulation of archaeal proteasome gate opening as studied by TROSY NMRSolution Structure of the 128 kDa Enzyme I Dimer from Escherichia coli and Its 146 kDa Complex with HPr Using Residual Dipolar Couplings and Small- and Wide-Angle X-ray ScatteringEngineering specificity in a dynamic protein complex with a single conserved mutationCharacterizing solution surface loop conformational flexibility of the GM2 activator protein.The low-affinity complex of cytochrome c and its peroxidaseLysine120 interactions with p53 response elements can allosterically direct p53 organization.Mechanistic details of a protein-protein association pathway revealed by paramagnetic relaxation enhancement titration measurements.Theory, practice, and applications of paramagnetic relaxation enhancement for the characterization of transient low-population states of biological macromolecules and their complexes.Ligand-free open-closed transitions of periplasmic binding proteins: the case of glutamine-binding protein.A rigid disulfide-linked nitroxide side chain simplifies the quantitative analysis of PRE data.Visualizing transient dark states by NMR spectroscopy.Exploring sparsely populated states of macromolecules by diamagnetic and paramagnetic NMR relaxation.The binding process of a nonspecific enzyme with DNA.Exploring translocation of proteins on DNA by NMRPulsed EPR characterization of HIV-1 protease conformational sampling and inhibitor-induced population shifts.The potential impact of recent developments in three-dimensional quantitative interaction proteomics on structural biology.Using multiple quantum coherence to increase the 15N resolution in a three-dimensional TROSY HNCO experiment for accurate PRE and RDC measurements.NMR spectroscopy brings invisible protein states into focus.Encounter complexes and dimensionality reduction in protein-protein association.Protein functional landscapes, dynamics, allostery: a tortuous path towards a universal theoretical framework.Dynamics in electron transfer protein complexes.Hybrid Approaches to Structural Characterization of Conformational Ensembles of Complex Macromolecular Systems Combining NMR Residual Dipolar Couplings and Solution X-ray Scattering.Protein dynamics and function from solution state NMR spectroscopy.Challenges in structural approaches to cell modeling.Identification of productive and futile encounters in an electron transfer protein complex.Mapping the encounter state of a transient protein complex by PRE NMR spectroscopy.Analysis of the solution conformations of T4 lysozyme by paramagnetic NMR spectroscopy.Photoinitiated singlet and triplet electron transfer across a redesigned [myoglobin, cytochrome b5] interface.Simultaneous detection of intra- and inter-molecular paramagnetic relaxation enhancements in protein complexes.Protein docking refinement by convex underestimation in the low-dimensional subspace of encounter complexes.Site-Mutation of Hydrophobic Core Residues Synchronically Poise Super Interleukin 2 for Signaling: Identifying Distant Structural Effects through Affordable Computations.
P2860
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P2860
Visualizing lowly-populated regions of the free energy landscape of macromolecular complexes by paramagnetic relaxation enhancement
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Visualizing lowly-populated re ...... agnetic relaxation enhancement
@ast
Visualizing lowly-populated re ...... agnetic relaxation enhancement
@en
type
label
Visualizing lowly-populated re ...... agnetic relaxation enhancement
@ast
Visualizing lowly-populated re ...... agnetic relaxation enhancement
@en
prefLabel
Visualizing lowly-populated re ...... agnetic relaxation enhancement
@ast
Visualizing lowly-populated re ...... agnetic relaxation enhancement
@en
P2860
P356
P1433
P1476
Visualizing lowly-populated re ...... agnetic relaxation enhancement
@en
P2093
G Marius Clore
P2860
P304
P356
10.1039/B810232E
P577
2008-09-02T00:00:00Z