Regulation of Fto/Ftm gene expression in mice and humans. - Wikidata - awgldk - TriplyDB

Regulation of Fto/Ftm gene expression in mice and humans.

Regulation of Fto/Ftm gene expression in mice and humans.

http://www.wikidata.org/entity/Q33599999

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The bigger picture of FTO: the first GWAS-identified obesity gene Hypothalamic FTO is associated with the regulation of energy intake not feeding reward Molecular physiology of weight regulation in mice and humans Six new loci associated with body mass index highlight a neuronal influence on body weight regulation Adult onset global loss of the fto gene alters body composition and metabolism in the mouse Obesity-associated variants within FTO form long-range functional connections with IRX3 Scrutinizing the FTO locus: compelling evidence for a complex, long-range regulatory context The FTO gene and measured food intake in children The fat mass- and obesity-associated locus and dietary intake in children The obesity-associated polymorphisms FTO rs9939609 and MC4R rs17782313 and endometrial cancer risk in non-Hispanic white women Genome-wide association analysis of body mass in chronic obstructive pulmonary disease.Nutrigenetics and nutrigenomics insights into diabetes etiopathogenesis.Obesity genes: so close and yet so far...Prevalence of loss-of-function FTO mutations in lean and obese individuals Association of genetic polymorphism of PPARγ-2, ACE, MTHFR, FABP-2 and FTO genes in risk prediction of type 2 diabetes mellitus Recent progress in the genetics of common obesity Genetic variation at the FTO locus influences RBL2 gene expression.Metabolic syndrome: from epidemiology to systems biology.FTO genotype is associated with exercise training-induced changes in body composition.Associations between an obesity related genetic variant (FTO rs9939609) and prostate cancer risk.From monogenic to polygenic obesity: recent advances.Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development.FTO gene polymorphisms and obesity risk: a meta-analysis.Fine mapping of the association with obesity at the FTO locus in African-derived populations.The genetics of obesity: FTO leads the way.Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice.Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway The fat mass and obesity associated gene, FTO, is also associated with osteoporosis phenotypes FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting.Fat mass and obesity-associated (FTO) gene polymorphisms are associated with physical activity, food intake, eating behaviors, psychological health, and modeled change in body mass index in overweight/obese Caucasian adults A link between FTO, ghrelin, and impaired brain food-cue responsivity.The biology of FTO: from nucleic acid demethylase to amino acid sensor.FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction.Overexpression of Fto leads to increased food intake and results in obesity State-of-the-art measurements in human body composition: A moving frontier of clinical importance.Association of genes with physiological functions by comparative analysis of pooled expression microarray data.The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation.Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling.Fat mass and obesity associated gene (FTO) expression is regulated negatively by the transcription factor Foxa2.

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P2860

Regulation of Fto/Ftm gene expression in mice and humans.

http://www.wikidata.org/entity/Q33599999

description

2008 nî lūn-bûn

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2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի փետրվարին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Regulation of Fto/Ftm gene expression in mice and humans.

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Regulation of Fto/Ftm gene expression in mice and humans.

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type

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Regulation of Fto/Ftm gene expression in mice and humans.

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Regulation of Fto/Ftm gene expression in mice and humans.

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prefLabel

Regulation of Fto/Ftm gene expression in mice and humans.

@ast

Regulation of Fto/Ftm gene expression in mice and humans.

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AJPREGU.00839.2007

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American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

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Regulation of Fto/Ftm gene expression in mice and humans.

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P2093

Charles A LeDuc

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Elizabeth Watson

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George Stratigopoulos

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Lori M Zeltser

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Rudolph L Leibel

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Stephanie L Padilla

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Wendy K Chung

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P2860

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

Species-specific subcellular localization of RPGR and RPGRIP isoforms: implications for the phenotypic variability of congenital retinopathies among species

Human CCAAT displacement protein is homologous to the Drosophila homeoprotein, cut

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

Assembly of centrosomal proteins and microtubule organization depends on PCM-1

Cloning of Fatso (Fto), a novel gene deleted by the Fused toes (Ft) mouse mutation

Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development

Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin.

Variation in FTO contributes to childhood obesity and severe adult obesity

The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle

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R1185-96

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10.1152/AJPREGU.00839.2007

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4

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Andrew Tym Hattersley

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2008-02-06T00:00:00Z

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5596358

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