Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus. - Wikidata - awgldk - TriplyDB

Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus.

Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus.

http://www.wikidata.org/entity/Q33494641

about

Use of a bacteriophage lysin to identify a novel target for antimicrobial development A widespread family of bacterial cell wall assembly proteins Selective small-molecule inhibition of an RNA structural element Two-component system cross-regulation integrates Bacillus anthracis response to heme and cell envelope stress Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets Efficacy of ampicillin against methicillin-resistant Staphylococcus aureus restored through synergy with branched poly(ethylenimine)Wall teichoic acids mediate increased virulence in Staphylococcus aureus.Development of an activity assay for discovery of inhibitors of lipopolysaccharide transport.Development of improved inhibitors of wall teichoic acid biosynthesis with potent activity against Staphylococcus aureus.Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2009.Induction kinetics of the Staphylococcus aureus cell wall stress stimulon in response to different cell wall active antibiotics Multidrug evolutionary strategies to reverse antibiotic resistance.ε/ζ systems: their role in resistance, virulence, and their potential for antibiotic development.Synthetic lethal compound combinations reveal a fundamental connection between wall teichoic acid and peptidoglycan biosyntheses in Staphylococcus aureus Validation of inhibitors of an ABC transporter required to transport lipopolysaccharide to the cell surface in Escherichia coli.ABC transporters required for export of wall teichoic acids do not discriminate between different main chain polymers.Role of wall teichoic acids in Staphylococcus aureus endophthalmitis.Discovery of novel cell wall-active compounds using P ywaC, a sensitive reporter of cell wall stress, in the model gram-positive bacterium Bacillus subtilis High-throughput assessment of bacterial growth inhibition by optical density measurements.An antibiotic that inhibits a late step in wall teichoic acid biosynthesis induces the cell wall stress stimulon in Staphylococcus aureus.Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase.Multidrug Intrinsic Resistance Factors in Staphylococcus aureus Identified by Profiling Fitness within High-Diversity Transposon Libraries.The Listeria monocytogenes PASTA Kinase PrkA and Its Substrate YvcK Are Required for Cell Wall Homeostasis, Metabolism, and Virulence Wall teichoic acid protects Staphylococcus aureus from inhibition by Congo red and other dyes.Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents.Wall teichoic acids of gram-positive bacteria.Wall teichoic acid function, biosynthesis, and inhibition.Chemical tools to discover and target bacterial glycoproteins.Antibiotics as probes of biological complexity.Bugs, drugs and chemical genomics.Inhibitors targeting on cell wall biosynthesis pathway of MRSA.Viable screening targets related to the bacterial cell wall.Teichoic acid biosynthesis as an antibiotic target.Taking aim at wall teichoic acid synthesis: new biology and new leads for antibiotics.Antiadhesion agents against Gram-positive pathogens.The Staphylococcus aureus Methicillin Resistance Factor FmtA Is a d-Amino Esterase That Acts on Teichoic Acids Antibiotic resistance in Staphylococcus aureus. Current status and future prospects.An update on the use of C. elegans for preclinical drug discovery: screening and identifying anti-infective drugs.Cell differentiation defines acute and chronic infection cell types in Staphylococcus aureus.Antibiotic That Inhibits the ATPase Activity of an ATP-Binding Cassette Transporter by Binding to a Remote Extracellular Site.

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P2860

Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus.

http://www.wikidata.org/entity/Q33494641

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Discovery of a small molecule ...... esis in Staphylococcus aureus.

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Discovery of a small molecule ...... esis in Staphylococcus aureus.

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type

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Discovery of a small molecule ...... esis in Staphylococcus aureus.

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Discovery of a small molecule ...... esis in Staphylococcus aureus.

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Discovery of a small molecule ...... esis in Staphylococcus aureus.

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Discovery of a small molecule ...... esis in Staphylococcus aureus.

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ACS Chemical Biology

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Discovery of a small molecule ...... esis in Staphylococcus aureus.

@en

P2093

Amy J Malhowski

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Jennifer Campbell

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Jonathan G Swoboda

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Michael S Gilmore

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Roy Kishony

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Stephanie Brown

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Suzanne Walker

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Takashi Suzuki

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Timothy C Meredith

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P2860

Xanthomonas campestris pv. campestris gum mutants: effects on xanthan biosynthesis and plant virulence.

A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence

Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization

Teichoic and teichuronic acids: biosynthesis, assembly, and location

Effect of wzx (rfbX) mutations on A-band and B-band lipopolysaccharide biosynthesis in Pseudomonas aeruginosa O5

Targeting QseC signaling and virulence for antibiotic development.

Identification, evolution, and essentiality of the mevalonate pathway for isopentenyl diphosphate biosynthesis in gram-positive cocci.

Accumulation of the enterobacterial common antigen lipid II biosynthetic intermediate stimulates degP transcription in Escherichia coli.

Current understanding on biosynthesis of microbial polysaccharides.

Biosynthesis of cell wall lipopolysaccharide in mutants of Salmonella. V. A mutant of Salmonella typhimurium defective in the synthesis of cytidine diphosphoabequose

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875-883

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scholarly article

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10.1021/CB900151K

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10

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4

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Tobias Bollenbach

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2009-10-01T00:00:00Z

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26749965

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19689117

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2787957

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