An OspB mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo.
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Outer surface protein B is critical for Borrelia burgdorferi adherence and survival within Ixodes ticksCharacterization of the physiological requirements for the bactericidal effects of a monoclonal antibody to OspB of Borrelia burgdorferi by confocal microscopyMolecular and immunological analyses of the Borrelia turicatae Bdr protein family.Protective immunity is induced by a Borrelia burgdorferi mutant that lacks OspA and OspB.DbpA, but not OspA, is expressed by Borrelia burgdorferi during spirochetemia and is a target for protective antibodiesCharacterization of Borrelia burgdorferi BlyA and BlyB proteins: a prophage-encoded holin-like systemPlasmid stability during in vitro propagation of Borrelia burgdorferi assessed at a clonal levelDissociation of infectivity and pathogenicity in Borrelia burgdorferiImpact of genotypic variation of Borrelia burgdorferi sensu stricto on kinetics of dissemination and severity of disease in C3H/HeJ mice.Clonal polymorphism of Borrelia burgdorferi strain B31 MI: implications for mutagenesis in an infectious strain backgroundGenome stability of Lyme disease spirochetes: comparative genomics of Borrelia burgdorferi plasmids.Genetics of Borrelia burgdorferiDifferential immune responses to Borrelia burgdorferi in European wild rodent species influence spirochete transmission to Ixodes ricinus L. (Acari: Ixodidae)In vivo activities of ceftriaxone and vancomycin against Borrelia spp. in the mouse brain and other sites.Effect of complement component C3 deficiency on experimental Lyme borreliosis in miceBorrelia burgdorferi mutant lacking Osp: biological and immunological characterization.Selection of variant Borrelia burgdorferi isolates from mice immunized with outer surface protein A or B.Molecular and evolutionary analyses of a variable series of genes in Borrelia burgdorferi that are related to ospE and ospF, constitute a gene family, and share a common upstream homology box.Directed insertion of a selectable marker into a circular plasmid of Borrelia burgdorferi.A bactericidal antibody to Borrelia burgdorferi is directed against a variable region of the OspB protein.Plasmid diversity and phylogenetic consistency in the Lyme disease agent Borrelia burgdorferi.Variability of a bacterial surface protein and disease expression in a possible mouse model of systemic Lyme borreliosis.Vaccination against Lyme disease caused by diverse Borrelia burgdorferiSimultaneous presence of different Borrelia burgdorferi genospecies in biological fluids of Lyme disease patientsExpression of outer surface proteins A and C of Borrelia burgdorferi in Ixodes ricinus.Whole-genome DNA array analysis of the response of Borrelia burgdorferi to a bactericidal monoclonal antibody.Disease severity in a murine model of lyme borreliosis is associated with the genotype of the infecting Borrelia burgdorferi sensu stricto strain.Abrogation of ospAB constitutively activates the Rrp2-RpoN-RpoS pathway (sigmaN-sigmaS cascade) in Borrelia burgdorferi.Experimental assessment of the roles of linear plasmids lp25 and lp28-1 of Borrelia burgdorferi throughout the infectious cycleIdentification of a highly cross-reactive outer surface protein B epitope among diverse geographic isolates of Borrelia spp. causing Lyme disease.Chemotaxis in Borrelia burgdorferi.Surface exposure and species specificity of an immunoreactive domain of a 66-kilodalton outer membrane protein (P66) of the Borrelia spp. that cause Lyme disease.Complement-mediated serum sensitivity among spirochetes that cause Lyme disease.Glycosphingolipid-binding protein of Borrelia burgdorferi sensu lato.Characterization of Finnish Borrelia burgdorferi sensu lato isolates by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and with monoclonal antibodies.Genetic stability of Borrelia burgdorferi recovered from chronically infected immunocompetent mice.Function and evolution of plasmid-borne genes for pyrimidine biosynthesis in Borrelia spp.Horizontally acquired genes for purine salvage in Borrelia spp. causing relapsing feverTranslocation of Borrelia burgdorferi surface lipoprotein OspA through the outer membrane requires an unfolded conformation and can initiate at the C-terminus.Development of a single-plasmid-based regulatable gene expression system for Borrelia burgdorferi.
P2860
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P2860
An OspB mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo.
description
1993 nî lūn-bûn
@nan
1993 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
An OspB mutant of Borrelia bur ...... d reduced infectivity in vivo.
@ast
An OspB mutant of Borrelia bur ...... d reduced infectivity in vivo.
@en
type
label
An OspB mutant of Borrelia bur ...... d reduced infectivity in vivo.
@ast
An OspB mutant of Borrelia bur ...... d reduced infectivity in vivo.
@en
prefLabel
An OspB mutant of Borrelia bur ...... d reduced infectivity in vivo.
@ast
An OspB mutant of Borrelia bur ...... d reduced infectivity in vivo.
@en
P2093
P2860
P1476
An OspB mutant of Borrelia bur ...... nd reduced infectivity in vivo
@en
P2093
A G Barbour
A Sadziene
D D Thomas
P2860
P304
P407
P577
1993-09-01T00:00:00Z