Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas. - Wikidata - awgldk - TriplyDB

Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas.

Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas.

http://www.wikidata.org/entity/Q33608757

about

Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation IL-21 Signaling in Immunity Interleukin-21 enhances rituximab activity in a cynomolgus monkey model of B cell depletion and in mouse B cell lymphoma models An overview on the role of dietary phenolics for the treatment of cancers Lymphoma: immune evasion strategies Interleukin-21 promotes thymopoiesis recovery following hematopoietic stem cell transplantation.New developments in the pathology of malignant lymphoma: a review of the literature published from October 2009 to January 2010 Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response Role of common-gamma chain cytokines in NK cell development and function: perspectives for immunotherapy.Antibody-cytokine fusion proteins for treatment of cancer: engineering cytokines for improved efficacy and safety.Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma.Direct and immune-mediated cytotoxicity of interleukin-21 contributes to antitumor effects in mantle cell lymphoma.Increased Th17 cells and IL-17A exist in patients with B cell acute lymphoblastic leukemia and promote proliferation and resistance to daunorubicin through activation of Akt signaling Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway.A phase I dose-finding trial of recombinant interleukin-21 and rituximab in relapsed and refractory low grade B-cell lymphoproliferative disorders Interleukin-21: a double-edged sword with therapeutic potential.IL-21: a pleiotropic cytokine with potential applications in oncology.Interleukin 21 - its potential role in the therapy of B-cell lymphomas.Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2.EBV counteracts IL-21-induced apoptosis in an EBV-positive diffuse large B-cell lymphoma cell line.Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo.Epstein-Barr virus (EBV) provides survival factors to EBV+ diffuse large B-cell lymphoma (DLBCL) lines and modulates cytokine induced specific chemotaxis in EBV+ DLBCL.Cytotoxic Epstein-Barr virus-positive large B cell lymphoma: a regulatory B cell-derived neoplasia?Effect of interleukin 21 and its receptor on CD8(+) T cells in the pathogenesis of diffuse large B-cell lymphoma.Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells Tissue microarray-based study of patients with lymph node-positive breast cancer shows tyrosine phosphorylation of signal transducer and activator of transcription 3 (tyrosine705-STAT3) is a marker of good prognosis.Tumor STAT3 tyrosine phosphorylation status, as a predictor of benefit from adjuvant chemotherapy for breast cancer.Gene expression analysis of plasmablastic lymphoma identifies downregulation of B-cell receptor signaling and additional unique transcriptional programs.Defective PTEN regulation contributes to B cell hyperresponsiveness in systemic lupus erythematosus.Recent advances in mantle cell lymphoma: report of the 2013 Mantle Cell Lymphoma Consortium Workshop.Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia.ALK-positive large B-cell lymphomas express a terminal B-cell differentiation program and activated STAT3 but lack MYC rearrangements.Systemic microRNA-34a delivery induces apoptosis and abrogates growth of diffuse large B-cell lymphoma in vivo.

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P2860

Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas.

http://www.wikidata.org/entity/Q33608757

description

2009 nî lūn-bûn

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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Novel IL-21 signaling pathway ...... iffuse large B-cell lymphomas.

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Novel IL-21 signaling pathway ...... diffuse large B-cell lymphomas

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P2093

Andrew J Gentles

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Eli Avisar

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Hovav Nechushtan

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Izidore S Lossos

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Raquel Malumbres

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P2860

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL

Myc pathways provoking cell suicide and cancer

The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3

Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease

Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation

Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production

Interleukin-21: a new modulator of immunity, infection, and cancer

IL-21 induces the functional maturation of murine NK cells

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40452647

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19965678

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2810990

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