Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis. - Wikidata - awgldk - TriplyDB

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.

http://www.wikidata.org/entity/Q41872521

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The Functional Role of PRC2 in Early T-cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) - Mechanisms and Opportunities Targeting EZH2 in cancer Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response EZH2 in normal hematopoiesis and hematological malignancies Epigenetic Codes Programing Class Switch Recombination The epigenetic basis of diffuse large B-cell lymphoma The genetic landscape of diffuse large B-cell lymphoma Novel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive review The role of aberrant proteolysis in lymphomagenesis EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis Diffuse large B-cell lymphoma: can genomics improve treatment options for a curable cancer?EZH2 alterations in follicular lymphoma: biological and clinical correlations.Regulation of germinal center responses and B-cell memory by the chromatin modifier MOZ The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.c-Rel regulates Ezh2 expression in activated lymphocytes and malignant lymphoid cells Regulation of germinal center, B-cell memory, and plasma cell formation by histone modifiers Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma.Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia Polycomb genes, miRNA, and their deregulation in B-cell malignancies The SWI/SNF chromatin remodeling complex regulates germinal center formation by repressing Blimp-1 expression.Dynamics of B cells in germinal centres.Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation YY1 Is Required for Germinal Center B Cell Development.Targeting EZH2 and PRC2 dependence as novel anticancer therapy.Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network.Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia Integrative Analysis Reveals the Transcriptional Collaboration between EZH2 and E2F1 in the Regulation of Cancer-Related Gene Expression Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity.Epigenetics of hematopoiesis and hematological malignancies.Investigational epigenetically targeted drugs in early phase trials for the treatment of haematological malignancies.The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?Role of the ubiquitin proteasome system in hematologic malignancies.An epigenetic view of B-cell disorders.Loss of RUNX3 expression is an independent adverse prognostic factor in diffuse large B-cell lymphoma.Epigenetic modifiers in normal and malignant hematopoiesis.The molecular pathogenesis of B-cell non-Hodgkin lymphoma.Context-dependent actions of Polycomb repressors in cancer.Epigenetic Control of B Cell Development and B-Cell-Related Immune Disorders.The importance of radiotherapy on diffuse large B cell lymphoma treatment: a current review.Cellular and chromatin dynamics of antibody-secreting plasma cells.

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P2860

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.

http://www.wikidata.org/entity/Q41872521

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.

@en

type

label

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.

@en

prefLabel

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.

@en

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Journal of Clinical Investigation

P1476

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis

@en

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Asoke K Talukder

http://www.w3.org/2001/XMLSchema#string

Chiara Carrisi

http://www.w3.org/2001/XMLSchema#string

Daisuke Kitamura

http://www.w3.org/2001/XMLSchema#string

Federica Alberghini

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Federica Mainoldi

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Federica Zanardi

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Gabriele Varano

http://www.w3.org/2001/XMLSchema#string

Laura George

http://www.w3.org/2001/XMLSchema#string

Luca Ferrarini

http://www.w3.org/2001/XMLSchema#string

Maurilio Ponzoni

http://www.w3.org/2001/XMLSchema#string

P2860

Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island

Plasma cell differentiation requires the transcription factor XBP-1

Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands

EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

PRC2 during vertebrate organogenesis: a complex in transition

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.

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5009-5022

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10.1172/JCI70626

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P433

12

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123

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Kai-Michael Toellner

Pierre-Luc Germain

Claudio Doglioni

Marieta Caganova

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2013-11-08T00:00:00Z

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258347179

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24200695

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3859423

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