Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury. - Wikidata - awgldk - TriplyDB

Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury.

Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury.

http://www.wikidata.org/entity/Q33613257

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Therapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorder Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury.What's New in Traumatic Brain Injury: Update on Tracking, Monitoring and Treatment Neurorestorative effect of urinary bladder matrix-mediated neural stem cell transplantation following traumatic brain injury in rats.A new avenue for lithium: intervention in traumatic brain injury.Scriptaid, a novel histone deacetylase inhibitor, protects against traumatic brain injury via modulation of PTEN and AKT pathway : scriptaid protects against TBI via AKT.Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts.Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancer HDAC inhibition in lupus models.The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet β cells in vivo and in vitro.HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis.Hdac-mediated control of endochondral and intramembranous ossification Preservation of the blood brain barrier and cortical neuronal tissue by liraglutide, a long acting glucagon-like-1 analogue, after experimental traumatic brain injury.Valproic Acid Neuroprotection in the 6-OHDA Model of Parkinson's Disease Is Possibly Related to Its Anti-Inflammatory and HDAC Inhibitory Properties.Lithium ameliorates neurodegeneration, suppresses neuroinflammation, and improves behavioral performance in a mouse model of traumatic brain injury.Hydroxamate-based histone deacetylase inhibitors can protect neurons from oxidative stress via a histone deacetylase-independent catalase-like mechanism.Lithium reduces BACE1 overexpression, β amyloid accumulation, and spatial learning deficits in mice with traumatic brain injury.Microglia in the TBI brain: The good, the bad, and the dysregulated.Epigenetic mechanisms in multiple sclerosis: implications for pathogenesis and treatment Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury Epigenetic changes following traumatic brain injury and their implications for outcome, recovery and therapy HDAC inhibitors in kidney development and disease.Anti-inflammatory Agents: Present and Future Omega-3 polyunsaturated fatty acid supplementation improves neurologic recovery and attenuates white matter injury after experimental traumatic brain injury.Epigenetics and the modulation of neuroinflammation.The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia.HDAC inhibitors and neurodegeneration: at the edge between protection and damage.Benefits of histone deacetylase inhibitors for acute brain injury: a systematic review of animal studies.Histone deacetylase inhibitors as therapeutic agents for acute central nervous system injuries.Glial epigenetics in neuroinflammation and neurodegeneration.Low dose of valproate improves motor function after traumatic brain injury.Enhancement of Autophagy by Histone Deacetylase Inhibitor Trichostatin A Ameliorates Neuronal Apoptosis After Subarachnoid Hemorrhage in Rats.The expression changes of cystathionine-β-synthase in brain cortex after traumatic brain injury.Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis.Uridine protects against hypoxic-ischemic brain injury by reducing histone deacetylase activity in neonatal rats.Potential immunotherapies for traumatic brain and spinal cord injury.

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P2860

Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury.

http://www.wikidata.org/entity/Q33613257

description

2009 nî lūn-bûn

@nan

2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

name

Histone deacetylase inhibitor ...... mental traumatic brain injury.

@ast

Histone deacetylase inhibitor ...... mental traumatic brain injury.

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type

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Histone deacetylase inhibitor ...... mental traumatic brain injury.

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Histone deacetylase inhibitor ...... mental traumatic brain injury.

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prefLabel

Histone deacetylase inhibitor ...... mental traumatic brain injury.

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Histone deacetylase inhibitor ...... mental traumatic brain injury.

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Histone deacetylase inhibitor ...... mental traumatic brain injury.

@en

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Alexander G Alexandrovich

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Athanasios Lourbopoulos

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Constantina Simeonidou

http://www.w3.org/2001/XMLSchema#string

Eleni Polyzoidou

http://www.w3.org/2001/XMLSchema#string

Esther Shohami

http://www.w3.org/2001/XMLSchema#string

Na'ama A Shein

http://www.w3.org/2001/XMLSchema#string

Nikolaos Grigoriadis

http://www.w3.org/2001/XMLSchema#string

Paolo Mascagni

http://www.w3.org/2001/XMLSchema#string

Victoria Trembovler

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P2860

Translating the Histone Code

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.

Heat shock proteins and protection of the nervous system

Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway

Targeting CREB-binding protein (CBP) loss of function as a therapeutic strategy in neurological disorders.

The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo

Traumatic brain injury: assessment, resuscitation and early management.

Induction of fetal globin in beta-thalassemia: Cellular obstacles and molecular progress.

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors.

Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease.

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4266-4275

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scholarly article

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10.1096/FJ.09-134700

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12

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23

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Charles A. Dinarello

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2009-09-01T00:00:00Z

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26783141

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19723705

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apoptotic process

traumatic brain injury

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2812044

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