Interstrand cross-links generated by abasic sites in duplex DNA.
about
Looking beneath the surface to determine what makes DNA damage deleteriousAdvances in understanding the complex mechanisms of DNA interstrand cross-link repairInterstrand cross-linking implies contrasting structural consequences for DNA: insights from molecular dynamics.On the formation and properties of interstrand DNA-DNA cross-links forged by reaction of an abasic site with the opposing guanine residue of 5'-CAp sequences in duplex DNA.Characterization of DNA damage induced by a natural product antitumor antibiotic leinamycin in human cancer cells.Synthesis of structurally diverse major groove DNA interstrand crosslinks using three different aldehyde precursors.Replication and repair of a reduced 2΄-deoxyguanosine-abasic site interstrand cross-link in human cells.Interstrand cross-links arising from strand breaks at true abasic sites in duplex DNA.Inhibition of short patch and long patch base excision repair by an oxidized abasic site.Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle.Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotidesNoncovalent DNA binding drives DNA alkylation by leinamycin: evidence that the Z,E-5-(thiazol-4-yl)-penta-2,4-dienone moiety of the natural product serves as an atypical DNA intercalator.A simple, high-yield synthesis of DNA duplexes containing a covalent, thermally cleavable interstrand cross-link at a defined locationThe macrocycle of leinamycin imparts hydrolytic stability to the thiol-sensing 1,2-dithiolan-3-one 1-oxide unit of the natural productMutagenic Bypass of an Oxidized Abasic Lesion-Induced DNA Interstrand Cross-Link Analogue by Human Translesion Synthesis DNA PolymerasesChemical structure and properties of interstrand cross-links formed by reaction of guanine residues with abasic sites in duplex DNASynthesis and characterization of a small analogue of the anticancer natural product leinamycin.DNA interstrand crosslink repair and cancer.DNA polymerase λ inactivation by oxidized abasic sites.Characterization of Interstrand DNA-DNA Cross-Links Using the α-Hemolysin Protein NanoporeCharacterization of Interstrand DNA-DNA Cross-Links Derived from Abasic Sites Using Bacteriophage ϕ29 DNA Polymerase.Nucleosome core particle-catalyzed strand scission at abasic sites.Site-specific inter-strand cross-links of DNA duplexes.Effective molarity in a nucleic acid-controlled reactionSimple, High-Yield Syntheses of DNA Duplexes Containing Interstrand DNA-DNA Cross-Links Between an N(4) -Aminocytidine Residue and an Abasic SiteScope and mechanism of interstrand cross-link formation by the C4'-oxidized abasic site.Possible chemical mechanisms underlying the antitumor activity of S-deoxyleinamycin.DNA interstrand cross-link formation by the 1,4-dioxobutane abasic lesionAn overview of chemical processes that damage cellular DNA: spontaneous hydrolysis, alkylation, and reactions with radicals.Abasic and oxidized abasic site reactivity in DNA: enzyme inhibition, cross-linking, and nucleosome catalyzed reactions.Interstrand DNA-DNA cross-link formation between adenine residues and abasic sites in duplex DNA.Epimeric 2-deoxyribose lesions: Products from the improper chemical repair of 2-deoxyribose radicals.Radiation-mediated formation of complex damage to DNA: a chemical aspect overview.DNA Interstrand Crosslinks by H-pin Polyamide (S)-seco-CBI Conjugates.A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA cross-links derived from psoralen and abasic sites.Base excision repair enzymes protect abasic sites in duplex DNA from interstrand cross-linksEffects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures.Sequence-Specific Covalent Capture Coupled with High-Contrast Nanopore Detection of a Disease-Derived Nucleic Acid Sequence.DNA-N-glycosylases process novel O-glycosidic sites in DNA.Crystal structure of a nucleoside model for the inter-strand cross-link formed by the reaction of 2'-de-oxy-guanosine and an abasic site in duplex DNA.
P2860
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P2860
Interstrand cross-links generated by abasic sites in duplex DNA.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Interstrand cross-links generated by abasic sites in duplex DNA.
@ast
Interstrand cross-links generated by abasic sites in duplex DNA.
@en
type
label
Interstrand cross-links generated by abasic sites in duplex DNA.
@ast
Interstrand cross-links generated by abasic sites in duplex DNA.
@en
prefLabel
Interstrand cross-links generated by abasic sites in duplex DNA.
@ast
Interstrand cross-links generated by abasic sites in duplex DNA.
@en
P2093
P2860
P356
P1476
Interstrand cross-links generated by abasic sites in duplex DNA.
@en
P2093
Goutam Chowdhury
Kent S Gates
Sanjay Dutta
P2860
P304
P356
10.1021/JA067294U
P407
P577
2007-01-25T00:00:00Z