A further investigation and reappraisal of the thio effect in the cleavage reaction catalyzed by a hammerhead ribozyme.
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Recent advances in the elucidation of the mechanisms of action of ribozymesA Two-Metal-Ion-Mediated Conformational Switching Pathway for HDV Ribozyme ActivationCHARMM force field parameters for simulation of reactive intermediates in native and thio-substituted ribozymesExistence of efficient divalent metal ion-catalyzed and inefficient divalent metal ion-independent channels in reactions catalyzed by a hammerhead ribozymeMeasurements of weak interactions between truncated substrates and a hammerhead ribozyme by competitive kinetic analyses: implications for the design of new and efficient ribozymes with high sequence specificity.Significantly higher activity of a cytoplasmic hammerhead ribozyme than a corresponding nuclear counterpart: engineered tRNAs with an extended 3' end can be exported efficiently and specifically to the cytoplasm in mammalian cellsComparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations.Biologically important reactions catalyzed by RNA molecules.Human topoisomerase IIalpha uses a two-metal-ion mechanism for DNA cleavage.Importance in catalysis of a magnesium ion with very low affinity for a hammerhead ribozyme.Relationships between the activities in vitro and in vivo of various kinds of ribozyme and their intracellular localization in mammalian cells.Mapping of the functional phosphate groups in the catalytic core of deoxyribozyme 10-23.
P2860
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P2860
A further investigation and reappraisal of the thio effect in the cleavage reaction catalyzed by a hammerhead ribozyme.
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2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
A further investigation and re ...... yzed by a hammerhead ribozyme.
@ast
A further investigation and re ...... yzed by a hammerhead ribozyme.
@en
type
label
A further investigation and re ...... yzed by a hammerhead ribozyme.
@ast
A further investigation and re ...... yzed by a hammerhead ribozyme.
@en
prefLabel
A further investigation and re ...... yzed by a hammerhead ribozyme.
@ast
A further investigation and re ...... yzed by a hammerhead ribozyme.
@en
P2860
P356
P1476
A further investigation and re ...... yzed by a hammerhead ribozyme.
@en
P2093
P2860
P304
P356
10.1093/NAR/28.8.1730
P407
P577
2000-04-01T00:00:00Z