Targeting the undruggable proteome: the small molecules of my dreams.
about
miRNA interventions serve as 'magic bullets' in the reversal of glioblastoma hallmarksHuman isoprenoid synthase enzymes as therapeutic targetsDissecting Fragment-Based Lead Discovery at the von Hippel-Lindau Protein:Hypoxia Inducible Factor 1α Protein-Protein InterfaceDiversity-oriented synthetic strategy for developing a chemical modulator of protein-protein interactionIdentification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.A bidirectional system for the dynamic small molecule control of intracellular fusion proteins.Hybrid compounds: from simple combinations to nanomachines.Identification of hydrophobic tags for the degradation of stabilized proteins.A HaloTag-based small molecule microarray screening methodology with increased sensitivity and multiplex capabilities.Induced protein degradation: an emerging drug discovery paradigm.Biophysical screening for the discovery of small-molecule ligands.Developing microRNA screening as a functional genomics tool for disease research.Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins.Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic TaggingCombined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor.Induced pluripotent stem cells in cardiovascular drug discovery.Neurotrophic natural products: chemistry and biology.The impact of network biology in pharmacology and toxicology.Small-molecule control of intracellular protein levels through modulation of the ubiquitin proteasome systemOverview of Recent Progress in Protein-Expression Technologies for Small-Molecule Screening.Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer.Metal-based drugs that break the rules.Ube2V2 Is a Rosetta Stone Bridging Redox and Ubiquitin Codes, Coordinating DNA Damage Responses.Targeted Intracellular Delivery of Antibodies: The State of the Art
P2860
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P2860
Targeting the undruggable proteome: the small molecules of my dreams.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Targeting the undruggable proteome: the small molecules of my dreams.
@ast
Targeting the undruggable proteome: the small molecules of my dreams.
@en
type
label
Targeting the undruggable proteome: the small molecules of my dreams.
@ast
Targeting the undruggable proteome: the small molecules of my dreams.
@en
prefLabel
Targeting the undruggable proteome: the small molecules of my dreams.
@ast
Targeting the undruggable proteome: the small molecules of my dreams.
@en
P2860
P1476
Targeting the undruggable proteome: the small molecules of my dreams.
@en
P2093
Craig M Crews
P2860
P304
P356
10.1016/J.CHEMBIOL.2010.05.011
P577
2010-06-01T00:00:00Z