Integrated analysis of germline and somatic variants in ovarian cancer. - Wikidata - awgldk - TriplyDB

Integrated analysis of germline and somatic variants in ovarian cancer.

Integrated analysis of germline and somatic variants in ovarian cancer.

http://www.wikidata.org/entity/Q33630954

about

Genomic/Epigenomic Alterations in Ovarian Carcinoma: Translational Insight into Clinical Practice The biological effects and clinical implications of BRCA mutations: where do we go from here?The genetics of breast cancer risk in the post-genome era: thoughts on study design to move past BRCA and towards clinical relevance Age-related mutations associated with clonal hematopoietic expansion and malignancies Patterns of somatically acquired amplifications and deletions in apparently normal tissues of ovarian cancer patients Advances in tumor screening, imaging, and avatar technologies for high-grade serous ovarian cancer.Copy number analysis of whole-genome data using BIC-seq2 and its application to detection of cancer susceptibility variants.Meta-dimensional data integration identifies critical pathways for susceptibility, tumorigenesis and progression of endometrial cancer Distinct implications of different BRCA mutations: efficacy of cytotoxic chemotherapy, PARP inhibition and clinical outcome in ovarian cancer Involvement of Chromatin Remodeling Genes and the Rho GTPases RhoB and CDC42 in Ovarian Clear Cell Carcinoma.A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data Pan-cancer analysis reveals technical artifacts in TCGA germline variant calls Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA.The NF1 somatic mutational landscape in sporadic human cancers.Functional proteomics of the epigenetic regulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medicine.Association between targeted somatic mutation (TSM) signatures and HGS-OvCa progression Characterization and identification of hidden rare variants in the human genome.Initial testing (stage 1) of the PARP inhibitor BMN 673 by the pediatric preclinical testing program: PALB2 mutation predicts exceptional in vivo response to BMN 673.Somatic microsatellite variability as a predictive marker for colorectal cancer and liver cancer progression.The promise and challenge of ovarian cancer models.An improved understanding of cancer genomics through massively parallel sequencing.The protein phosphatase 2A inhibitor LB100 sensitizes ovarian carcinoma cells to cisplatin-mediated cytotoxicity Precision Nanomedicine Using Dual PET and MR Temperature Imaging-Guided Photothermal Therapy.Loss of Mll3 Catalytic Function Promotes Aberrant Myelopoiesis Identification, genetic testing, and management of hereditary melanoma.Patterns and functional implications of rare germline variants across 12 cancer types REPURPOSING GERMLINE EXOMES OF THE CANCER GENOME ATLAS DEMANDS A CAUTIOUS APPROACH AND SAMPLE-SPECIFIC VARIANT FILTERING Genetic and molecular changes in ovarian cancer.Primary Peritoneal Carcinoma in a BRCA1/2-negative, PALB2-positive patient.Systematic discovery of complex insertions and deletions in human cancers.dbCPG: A web resource for cancer predisposition genes.Concordance between somatic copy number loss and down-regulated expression: A pan-cancer study of cancer predisposition genes.Novel BRCA1 and BRCA2 Tumor Test as Basis for Treatment Decisions and Referral for Genetic Counselling of Patients with Ovarian Carcinomas.Simultaneous detection of BRCA mutations and large genomic rearrangements in germline DNA and FFPE tumor samples.Therapeutic opportunities within the DNA damage response.GenomeVIP: a cloud platform for genomic variant discovery and interpretation.Mutation spectra of histone methyltransferases with canonical SET domains and EZH2-targeted therapy.Mutational heterogeneity in non-serous ovarian cancers.Germline mutations in DNA repair genes in lung adenocarcinoma.Establishment and characterization of a platinum- and paclitaxel-resistant high grade serous ovarian carcinoma cell line.

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Integrated analysis of germline and somatic variants in ovarian cancer.

http://www.wikidata.org/entity/Q33630954

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունվարին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Integrated analysis of germline and somatic variants in ovarian cancer.

@ast

Integrated analysis of germline and somatic variants in ovarian cancer.

@en

type

label

Integrated analysis of germline and somatic variants in ovarian cancer.

@ast

Integrated analysis of germline and somatic variants in ovarian cancer.

@en

prefLabel

Integrated analysis of germline and somatic variants in ovarian cancer.

@ast

Integrated analysis of germline and somatic variants in ovarian cancer.

@en

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Nature Communications

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Integrated analysis of germline and somatic variants in ovarian cancer

@en

P2093

Benjamin J Raphael

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Charles Lu

http://www.w3.org/2001/XMLSchema#string

Christopher A Miller

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Daniel C Koboldt

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David E Larson

http://www.w3.org/2001/XMLSchema#string

Elaine R Mardis

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Heather K Schmidt

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Joshua F McMichael

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Kimberly J Johnson

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Krishna L Kanchi

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P2860

iRefIndex: a consolidated protein interaction database with provenance

An integrated map of genetic variation from 1,092 human genomes

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

Comprehensive molecular portraits of human breast tumours

Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing

Genome-wide association study identifies novel breast cancer susceptibility loci

A census of human cancer genes

Somatic mutations affect key pathways in lung adenocarcinoma

Fast and accurate short read alignment with Burrows-Wheeler transform

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

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3156

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scholarly article

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10.1038/NCOMMS4156

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P478

5

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Timothy A. Graubert

Matthew A Wyczalkowski

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2014-01-01T00:00:00Z

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259846932

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1006523820

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24448499

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4025965

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