Selective repression of transcriptional activators by Pbx1 does not require the homeodomain
about
Functional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNAPBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteinsA conserved C-terminal domain in PBX increases DNA binding by the PBX homeodomain and is not a primary site of contact for the YPWM motif of HOXA1DNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complexCooperative transcriptional activation by Klf4, Meis2, and Pbx1An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activationThe role of E2A-PBX1 in leukemogenesis.Pre-B cell leukemia homeobox 1 is associated with lupus susceptibility in mice and humans.Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner.Cell signaling switches HOX-PBX complexes from repressors to activators of transcription mediated by histone deacetylases and histone acetyltransferases.Gtx, an oligodendrocyte-specific homeodomain protein, has repressor activity.The role of Pbx1 in T cells.Functional dissection of a transcriptionally active, target-specific Hox-Pbx complex.
P2860
Q22254126-DFF166DD-4F6C-4986-9356-02DF0A27F2F6Q24554397-389418A4-B2BE-487F-9050-6875852CE00CQ28270511-C4512798-5C67-46C2-9E7F-2B2183C996FCQ28591464-91BB2EFA-B418-4009-8483-E530A0A8A50CQ30428157-B27A5F43-3421-4E6F-9290-DBFAA2F0D01FQ32036980-065B9FA6-D3C5-4810-87C5-29B0D5566352Q33890284-14147C37-004D-4A76-A980-90696720A000Q34405471-5723EFED-B61C-47D4-A5F5-D913EA8E739DQ35658918-C56AFE57-D97A-4744-A254-3FFB14E533F1Q39449291-7DF3C73D-456E-4426-BD85-3E11CECFAB29Q39540142-B1424D6C-DFDC-40CB-9C57-B461CA026831Q40863557-100122F4-BADE-40D9-B8E6-C767EA6E7BA0Q41774425-70C62E96-026D-4350-9352-23531D5CF87FQ42066347-BA06CDB1-7F1A-48CE-9146-1AE1976C1B06
P2860
Selective repression of transcriptional activators by Pbx1 does not require the homeodomain
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Selective repression of transc ...... es not require the homeodomain
@ast
Selective repression of transc ...... es not require the homeodomain
@en
type
label
Selective repression of transc ...... es not require the homeodomain
@ast
Selective repression of transc ...... es not require the homeodomain
@en
prefLabel
Selective repression of transc ...... es not require the homeodomain
@ast
Selective repression of transc ...... es not require the homeodomain
@en
P2860
P356
P1476
Selective repression of transc ...... es not require the homeodomain
@en
P2860
P304
P356
10.1073/PNAS.93.1.470
P407
P577
1996-01-01T00:00:00Z