Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters.
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P1343
Self-organized Kidney Rudiments: Prospects for Better in vitro Nephrotoxicity AssaysLocalization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines.Transcriptional control of the multi-drug transporter ABCB1 by transcription factor Sp3 in different human tissuesEndo-lysosomal dysfunction in human proximal tubular epithelial cells deficient for lysosomal cystine transporter cystinosinUrinary kidney biomarkers for early detection of nephrotoxicity in clinical drug development.The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule.Optimized metabolomic approach to identify uremic solutes in plasma of stage 3-4 chronic kidney disease patients.Alkaline phosphatase protects against renal inflammation through dephosphorylation of lipopolysaccharide and adenosine triphosphate.A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity.Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients.Role of p-glycoprotein expression and function in cystinotic renal proximal tubular cellsThe pathogenesis of cystinosis: mechanisms beyond cystine accumulation.Podocyte culture: tricks of the trade.Glomerular involvement in the arthrogryposis, renal dysfunction and cholestasis syndrome.Human Urine as a Noninvasive Source of Kidney Cells.Transporter assays as useful in vitro tools in drug discovery and development.New insights into the effects of biomaterial chemistry and topography on the morphology of kidney epithelial cells.Human proximal tubule epithelial cells cultured on hollow fibers: living membranes that actively transport organic cationsConditionally immortalized human proximal tubular epithelial cells isolated from the urine of a healthy subject express functional calcium-sensing receptor.Cationic uremic toxins affect human renal proximal tubule cell functioning through interaction with the organic cation transporter.Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metformin.Renal Handling of Circulating and Renal-Synthesized Hepcidin and Its Protective Effects against Hemoglobin-Mediated Kidney Injury.Urine of Preterm Neonates as a Novel Source of Kidney Progenitor Cells.Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application.Uremic Toxins Induce ET-1 Release by Human Proximal Tubule Cells, which Regulates Organic Cation Uptake Time-Dependently.Cetuximab Prevents Methotrexate-Induced Cytotoxicity in Vitro through Epidermal Growth Factor Dependent Regulation of Renal Drug Transporters.Bioengineered kidney tubules efficiently excrete uremic toxins.Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment.Achievements and challenges in bioartificial kidney development.Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions.Altered mTOR signalling in nephropathic cystinosis.A bioartificial environment for kidney epithelial cells based on a supramolecular polymer basement membrane mimic and an organotypical culture system.Advances in predictive in vitro models of drug-induced nephrotoxicity.Lithium induces mesenchymal-epithelial differentiation during human kidney development by activation of the Wnt signalling system.Quantification of cystine in human renal proximal tubule cells using liquid chromatography-tandem mass spectrometry.Activation of Calcium-Sensing Receptor increases intracellular calcium and decreases cAMP and mTOR in PKD1 deficient cells.Activation of the Calcium-Sensing Receptor Corrects the Impaired Mitochondrial Energy Status Observed in Renal Polycystin-1 Knockdown Cells Modeling Autosomal Dominant Polycystic Kidney Disease
P2860
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P2860
Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Novel conditionally immortaliz ...... nflux and efflux transporters.
@ast
Novel conditionally immortaliz ...... nflux and efflux transporters.
@en
type
label
Novel conditionally immortaliz ...... nflux and efflux transporters.
@ast
Novel conditionally immortaliz ...... nflux and efflux transporters.
@en
prefLabel
Novel conditionally immortaliz ...... nflux and efflux transporters.
@ast
Novel conditionally immortaliz ...... nflux and efflux transporters.
@en
P2093
P2860
P1476
Novel conditionally immortaliz ...... nflux and efflux transporters.
@en
P2093
Elena N Levtchenko
Frans G Russel
Lambertus P van den Heuvel
Leo A Monnens
Martijn J Wilmer
Moin A Saleem
Peter W Mathieson
Rosalinde Masereeuw
Thea J van der Velden
P2860
P2888
P304
P356
10.1007/S00441-009-0882-Y
P4510
P577
2009-11-10T00:00:00Z
P5875
P6179
1004331922