Characterisation of human tubular cell monolayers as a model of proximal tubular xenobiotic handling.
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Self-organized Kidney Rudiments: Prospects for Better in vitro Nephrotoxicity AssaysEndocytotic uptake of zoledronic acid by tubular cells may explain its renal effects in cancer patients receiving high doses of the compoundIsolation and characterization of a primary proximal tubular epithelial cell model from human kidney by CD10/CD13 double labelingNovel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters.The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule.Creatinine, arsenic metabolism, and renal function in an arsenic-exposed population in BangladeshA Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity.The right compound in the right assay at the right time: an integrated discovery DMPK strategy.Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics.In vitro and in vivo approaches to characterize transporter-mediated disposition in drug discovery.Transporter assays as useful in vitro tools in drug discovery and development.Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function.Evaluation and Quantitative Prediction of Renal Transporter-Mediated Drug-Drug Interactions.Pre-Plated Cell Lines for ADMETox Applications in the Pharmaceutical Industry.Novel minimal physiologically-based model for the prediction of passive tubular reabsorption and renal excretion clearance.Interleukin-19 as a translational indicator of renal injury.Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics.Acyclovir is a substrate for the human breast cancer resistance protein (BCRP/ABCG2): implications for renal tubular transport and acyclovir-induced nephrotoxicity.Calcein assay: a high-throughput method to assess P-gp inhibition.Development of a microphysiological model of human kidney proximal tubule function.Mechanistic models describing active renal reabsorption and secretion: a simulation-based study.Usefulness of kidney slices for functional analysis of apical reabsorptive transporters.Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms.Evaluation of the effects of AZD3480 on cardiac repolarization: a thorough QT/QTc study using moxifloxacin as a positive control.A Predominant Oxidative Renal Metabolite of Empagliflozin in Male Mice Is Cytotoxic in Mouse Renal Tubular Cells but not Genotoxic.The role of OAT2 (SLC22A7) in the cyclic nucleotide biokinetics of human erythrocytes.Applications of kidney organoids derived from human pluripotent stem cells.Solute Carrier (SLC) Family Transporters
P2860
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P2860
Characterisation of human tubular cell monolayers as a model of proximal tubular xenobiotic handling.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Characterisation of human tubu ...... l tubular xenobiotic handling.
@ast
Characterisation of human tubu ...... l tubular xenobiotic handling.
@en
type
label
Characterisation of human tubu ...... l tubular xenobiotic handling.
@ast
Characterisation of human tubu ...... l tubular xenobiotic handling.
@en
prefLabel
Characterisation of human tubu ...... l tubular xenobiotic handling.
@ast
Characterisation of human tubu ...... l tubular xenobiotic handling.
@en
P2093
P1476
Characterisation of human tubu ...... l tubular xenobiotic handling.
@en
P2093
Amy S Windass
Anja Verhulst
Colin D A Brown
Marc E De Broe
Patrick C D'Haese
Rachel Sayer
P304
P356
10.1016/J.TAAP.2008.09.018
P577
2008-10-01T00:00:00Z