Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells. - Wikidata - awgldk - TriplyDB

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

http://www.wikidata.org/entity/Q33634465

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pH regulation and beyond: unanticipated functions for the voltage-gated proton channel, HVCN1 A lesson for cancer research: placental microarray gene analysis in preeclampsia S1PR2 links germinal center confinement and growth regulation Interleukin-21 accelerates thymic recovery from glucocorticoïd-induced atrophy Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency The role of aberrant proteolysis in lymphomagenesis ARACNe-based inference, using curated microarray data, of Arabidopsis thaliana root transcriptional regulatory networks hARACNe: improving the accuracy of regulatory model reverse engineering via higher-order data processing inequality tests.Germinal center B cells recognize antigen through a specialized immune synapse architecture.Inferring protein modulation from gene expression data using conditional mutual information."Upstream Analysis": An Integrated Promoter-Pathway Analysis Approach to Causal Interpretation of Microarray Data.Neuroprotective pentapeptide CN-105 is associated with reduced sterile inflammation and improved functional outcomes in a traumatic brain injury murine model.Correlating measurements across samples improves accuracy of large-scale expression profile experiments.Germinal center B cell development has distinctly regulated stages completed by disengagement from T cell help Reverse-engineering human regulatory networks MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma.Expansion or depletion of T follicular helper cells during HIV infection: consequences for B cell responses.The generation of antibody-secreting plasma cells.Cyclin D3 is selectively required for proliferative expansion of germinal center B cells.ZFP36L1 negatively regulates plasmacytoid differentiation of BCL1 cells by targeting BLIMP1 mRNA.A negative selection heuristic to predict new transcriptional targets.Activation of B cells by a dendritic cell-targeted oral vaccine.Splice-correction strategies for treatment of X-linked agammaglobulinemia.Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma.Deletion of STAT5a/b in vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease.Kaposi's sarcoma-associated herpesvirus microRNAs repress breakpoint cluster region protein expression, enhance Rac1 activity, and increase in vitro angiogenesis.Elucidating Compound Mechanism of Action by Network Perturbation Analysis.Using systems and structure biology tools to dissect cellular phenotypes IFI16 Expression Is Related to Selected Transcription Factors during B-Cell Differentiation.Regulatory network reconstruction reveals genes with prognostic value for chronic lymphocytic leukemia.Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation.A Network Model to Describe the Terminal Differentiation of B Cells miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model BCL6 positively regulates AID and germinal center gene expression via repression of miR-155.Overcoming rituximab drug-resistance by the genetically engineered anti-CD20-hIFN-α fusion protein: Direct cytotoxicity and synergy with chemotherapy.Subtype-specific addiction of the activated B-cell subset of diffuse large B-cell lymphoma to FOXP1.IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells.Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms UCH-L1 is induced in germinal center B cells and identifies patients with aggressive germinal center diffuse large B-cell lymphoma.The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment

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Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

http://www.wikidata.org/entity/Q33634465

description

2009 nî lūn-bûn

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2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Integrated biochemical and com ...... ormal germinal center B cells.

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Integrated biochemical and com ...... ormal germinal center B cells.

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Integrated biochemical and com ...... ormal germinal center B cells.

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Integrated biochemical and com ...... ormal germinal center B cells.

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Integrated biochemical and com ...... normal germinal center B cells

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Adam A Margolin

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Christof Schneider

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Katia Basso

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Mariano J Alvarez

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Masumichi Saito

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Pavel Sumazin

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Riccardo Dalla-Favera

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Wei-Keat Lim

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Yukiko Kitagawa

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ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas

Human USP3 is a chromatin modifier required for S phase progression and genome stability

MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation

The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells

BCL-6 protein is expressed in germinal-center B cells

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Transcriptional analysis of the B cell germinal center reaction

General transcriptional coactivator PC4 activates p53 function

Genomic targets of the human c-Myc protein

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975-984

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10.1182/BLOOD-2009-06-227017

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5

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115

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Andrea Califano

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2009-12-03T00:00:00Z

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40452602

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