A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.

A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.

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http://www.wikidata.org/entity/Q33635514
Functions and regulation of the multitasking FANCM family of DNA motor proteinsFanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repairRescue from replication stress during mitosis.The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription.Endogenous DNA Damage Leads to p53-Independent Deficits in Replicative Fitness in Fetal Murine Fancd2(-/-) Hematopoietic Stem and Progenitor Cells.Simvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth.Human somatic cells deficient for RAD52 are impaired for viral integration and compromised for most aspects of homology-directed repair.FANCD2-controlled chromatin access of the Fanconi-associated nuclease FAN1 is crucial for the recovery of stalled replication forks.Order from clutter: selective interactions at mammalian replication origins.Dormant origins as a built-in safeguard in eukaryotic DNA replication against genome instability and disease development.Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation.Around and beyond 53BP1 Nuclear Bodies.Break induced replication in eukaryotes: mechanisms, functions, and consequences.
P2860

A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.

Item
http://www.wikidata.org/entity/Q33635514
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A concomitant loss of dormant ...... replication fork progression.
@ast
A concomitant loss of dormant ...... replication fork progression.
@en
type
label
A concomitant loss of dormant ...... replication fork progression.
@ast
A concomitant loss of dormant ...... replication fork progression.
@en
prefLabel
A concomitant loss of dormant ...... replication fork progression.
@ast
A concomitant loss of dormant ...... replication fork progression.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
A concomitant loss of dormant ...... A replication fork progression
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932