FANCD2-controlled chromatin access of the Fanconi-associated nuclease FAN1 is crucial for the recovery of stalled replication forks. - Wikidata - awgldk - TriplyDB

FANCD2-controlled chromatin access of the Fanconi-associated nuclease FAN1 is crucial for the recovery of stalled replication forks.

FANCD2-controlled chromatin access of the Fanconi-associated nuclease FAN1 is crucial for the recovery of stalled replication forks.

http://www.wikidata.org/entity/Q38964784

about

Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway Replication stress: getting back on track Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability FANCD2-associated nuclease 1, but not exonuclease 1 or flap endonuclease 1, is able to unhook DNA interstrand cross-links in vitro Crystal structure of human Fanconi-associated nuclease 1.Allyl isothiocyanate induces replication-associated DNA damage response in NSCLC cells and sensitizes to ionizing radiation.Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks.Identification of Genetic Factors that Modify Clinical Onset of Huntington's Disease.Rad51 recombinase prevents Mre11 nuclease-dependent degradation and excessive PrimPol-mediated elongation of nascent DNA after UV irradiation.Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair.Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies.The nuclease FAN1 is involved in DNA crosslink repair in Arabidopsis thaliana independently of the nuclease MUS81.FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5'-DNA end.Combining electron microscopy with single molecule DNA fiber approaches to study DNA replication dynamics.S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion.Arsenite Binds to the RING Finger Domain of FANCL E3 Ubiquitin Ligase and Inhibits DNA Interstrand Crosslink Repair.FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2 FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response.Building up and breaking down: mechanisms controlling recombination during replication.Structural mechanism of DNA interstrand cross-link unhooking by the bacterial FAN1 nuclease.Processing of DNA Ends in the Maintenance of Genome Stability Ubiquitylation at the Fork: Making and Breaking Chains to Complete DNA Replication

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FANCD2-controlled chromatin access of the Fanconi-associated nuclease FAN1 is crucial for the recovery of stalled replication forks.

http://www.wikidata.org/entity/Q38964784

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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2014年论文

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name

FANCD2-controlled chromatin ac ...... of stalled replication forks.

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type

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FANCD2-controlled chromatin ac ...... of stalled replication forks.

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prefLabel

FANCD2-controlled chromatin ac ...... of stalled replication forks.

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Molecular and Cellular Biology

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FANCD2-controlled chromatin ac ...... of stalled replication forks.

@en

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Alexandra Sobeck

http://www.w3.org/2001/XMLSchema#string

Daniel R Stroik

http://www.w3.org/2001/XMLSchema#string

Indrajit Chaudhury

http://www.w3.org/2001/XMLSchema#string

P2860

UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination.

BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

Molecular pathogenesis and clinical management of Fanconi anemia

Susceptibility pathways in Fanconi's anemia and breast cancer

Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging

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3939-3954

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scholarly article

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10.1128/MCB.00457-14

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21

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34

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2014-08-18T00:00:00Z

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25135477

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4386448

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