Cyclooxygenase-1 and -2 differentially modulate lipopolysaccharide-induced blood-brain barrier disruption through matrix metalloproteinase activity - Wikidata - awgldk - TriplyDB

Cyclooxygenase-1 and -2 differentially modulate lipopolysaccharide-induced blood-brain barrier disruption through matrix metalloproteinase activity

Cyclooxygenase-1 and -2 differentially modulate lipopolysaccharide-induced blood-brain barrier disruption through matrix metalloproteinase activity

http://www.wikidata.org/entity/Q33638396

about

Chemical dampening of Ly6C(hi) monocytes in the periphery produces anti-depressant effects in mice.Neuronal overexpression of cyclooxygenase-2 does not alter the neuroinflammatory response during brain innate immune activation.Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus Induction of COX-2 enzyme and down-regulation of COX-1 expression by lipopolysaccharide (LPS) control prostaglandin E2 production in astrocytes Targeting cyclooxygenases-1 and -2 in neuroinflammation: Therapeutic implications.p38α (MAPK14) critically regulates the immunological response and the production of specific cytokines and chemokines in astrocytes.COX1 and COX2 expression in non-neuronal cellular compartments of the rhesus macaque brain during lentiviral infection.Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes.Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects.Exendin-4 protected against cognitive dysfunction in hyperglycemic mice receiving an intrahippocampal lipopolysaccharide injection.The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis.Persistent neuroinflammatory effects of serial exposure to stress and methamphetamine on the blood-brain barrier.Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease.Targeting cyclooxygenase-2 in depression is not a viable therapeutic approach and may even aggravate the pathophysiology underpinning depression.Identification of highly connected hub genes in the protective response program of human macrophages and microglia activated by alpha B-crystallin.COX-1 and COX-2 polymorphisms in susceptibility to cerebral palsy in very preterm infants.Highly Selective Cyclooxygenase-1 Inhibitors P6 and Mofezolac Counteract Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation.Differential expression of E-type prostanoid receptors 2 and 4 in microglia stimulated with lipopolysaccharide.Genetic and Histological Alterations Reveal Key Role of Prostaglandin Synthase and Cyclooxygenase 1 and 2 in Traumatic Brain Injury-Induced Neuroinflammation in the Cerebral Cortex of Rats Exposed to Moderate Fluid Percussion Injury.Impairment of Rat Spatial Learning and Memory in a New Model of Cold Water-Induced Chronic Hypothermia: Implication for Alzheimer's Disease.Dexamethasone inhibits ICAM-1 and MMP-9 expression and reduces brain edema in intracerebral hemorrhagic rats.

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P2860

Cyclooxygenase-1 and -2 differentially modulate lipopolysaccharide-induced blood-brain barrier disruption through matrix metalloproteinase activity

http://www.wikidata.org/entity/Q33638396

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Cyclooxygenase-1 and -2 differ ...... rix metalloproteinase activity

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Cyclooxygenase-1 and -2 differ ...... rix metalloproteinase activity

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type

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Cyclooxygenase-1 and -2 differ ...... rix metalloproteinase activity

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Cyclooxygenase-1 and -2 differ ...... rix metalloproteinase activity

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Cyclooxygenase-1 and -2 differ ...... rix metalloproteinase activity

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Cyclooxygenase-1 and -2 differ ...... rix metalloproteinase activity

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P1433

Journal of Cerebral Blood Flow & Metabolism

P1476

Cyclooxygenase-1 and -2 differ ...... rix metalloproteinase activity

@en

P2093

Afonso C Silva

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Francesca Bosetti

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Gary A Rosenberg

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Saba Aid

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Sang-Ho Choi

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P2860

Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain

Neuronal oxidative damage and dendritic degeneration following activation of CD14-dependent innate immune response in vivo

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Blood-brain barrier disruption by stromelysin-1 facilitates neutrophil infiltration in neuroinflammation

Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data

Gene expression of cyclooxygenase-1 and Ca(2+)-independent phospholipase A(2) is altered in rat hippocampus during normal aging

Cyclooxygenase inhibition limits blood-brain barrier disruption following intracerebral injection of tumor necrosis factor-alpha in the rat

The blood-brain barrier in health and chronic neurodegenerative disorders

Interleukin-1beta -induced changes in blood-brain barrier permeability, apparent diffusion coefficient, and cerebral blood volume in the rat brain: a magnetic resonance study.

Cyclooxygenase-1 participates in selected vasodilator responses of the cerebral circulation.

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370-380

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scholarly article

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10.1038/JCBFM.2009.223

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2

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30

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Eduardo Candelario-Jalil

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2009-10-21T00:00:00Z

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38025205

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19844242

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P921

blood–brain barrier

lipopolysaccharide

P932

2818570

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