Late sodium current block for drug-induced long QT syndrome: Results from a prospective clinical trial
about
Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current BlockAutomated Algorithm for J-Tpeak and Tpeak-Tend Assessment of Drug-Induced Proarrhythmia RiskA computational model predicts adjunctive pharmacotherapy for cardiac safety via selective inhibition of the late cardiac Na current.Increased Late Sodium Current Contributes to the Electrophysiological Effects of Chronic, but Not Acute, Dofetilide Administration.Clinical Trials in a DishDrug-Induced QT/QTc Interval Shortening: Lessons from Drug-Induced QT/QTc Prolongation.Traditional and novel electrocardiographic conduction and repolarization markers of sudden cardiac death.Synergistic Effect of Dofetilide and Mexiletine on Prevention of Atrial Fibrillation.Commentary on: "Levofloxacin-Induced QTc Prolongation Depends on the Time of Drug Administration".Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk AssessmentMechanistic Model-Informed Proarrhythmic Risk Assessment of Drugs: Review of the "CiPA" Initiative and Design of a Prospective Clinical Validation Study.Nonclinical cardiovascular safety of pitolisant: comparing International Conference on Harmonization S7B and Comprehensive in vitro Pro-arrhythmia Assay initiative studies.Adult Human Primary Cardiomyocyte-Based Model for the Simultaneous Prediction of Drug-Induced Inotropic and Pro-arrhythmia Risk.Scientific white paper on concentration-QTc modeling.An evaluation of multiple algorithms for the measurement of the heart rate corrected JTpeak interval.Observations on conducting whole-cell patch clamping of the hERG cardiac K+ channel in pure human serum.Chirality sensing of bioactive compounds with amino alcohol unit via circular dichroism.Minimal T-wave representation and its use in the assessment of drug arrhythmogenicity.Recent developments in the science of proarrhythmic cardiac safety of new drugs.Comprehensive Translational Assessment of Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias.Translating New Science Into the Drug Review Process: The US FDA's Division of Applied Regulatory Science.International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential AssessmentNoninvasive assessment of dofetilide plasma concentration using a deep learning (neural network) analysis of the surface electrocardiogram: A proof of concept studyPredictive Value of T - T Indices for Adverse Outcomes in Acquired QT Prolongation: A Meta-Analysis
P2860
Q28468470-1973EF2A-5A9A-4339-B674-CB7A518A53F9Q28468489-61D7B947-0F12-4FB2-B580-B3E8613A9DA5Q33751744-5B92DE2D-17ED-42A8-A061-6A1BC3CE0B32Q36851520-F443B575-E418-476E-9BBB-2EA0881C0C97Q37737063-A12DE8A9-E682-4B5A-A810-0D726D14772FQ38770432-C8E0546E-551A-496E-B72E-6BF49E7137A9Q38972230-BE4DE469-B34F-4066-B702-FD24671C568AQ41104424-75BADF44-963E-4DBD-872B-2A4A918D3E8DQ41181870-AE4AA694-E217-4DF1-8ABE-DC081F0517B5Q41524806-E6E82B93-57D3-43E5-B4F3-12800F5F256BQ45981926-91800F15-A51F-46D9-AC62-34415742F653Q47135264-907F2FF4-D1E2-4FEC-9C4F-A3E318719617Q47194598-B8BC6B15-55AB-4ECC-84C9-EAC82EE8BC7CQ47361141-B60D5ACD-C313-466F-B3D4-247F43D75FC9Q47579240-769C79E6-70C5-494C-922F-F2FDC598E064Q48017483-A6B358D6-0EB3-4046-A107-AA903AC59B00Q48297250-0957A8C1-1847-4EBB-B156-74659D748EB3Q50559385-26E32E15-BE41-4C6E-B84A-837938D40A6CQ50665549-C963A121-7E07-409D-8F84-E4151F40AA78Q51146786-89098296-0AD0-4DD0-B55D-9E258D44E464Q52641412-C72DA66D-1D5B-4602-AC9F-D497CDF7A54CQ58696730-A942C745-8455-4833-8636-1697C3853E54Q58723630-D2DF783A-1B4A-40C7-83FC-DAC1FF71457DQ58767340-196668EF-2C2F-4A2E-9470-01A4243AF9D1
P2860
Late sodium current block for drug-induced long QT syndrome: Results from a prospective clinical trial
description
2015 nî lūn-bûn
@nan
2015 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Late sodium current block for ...... m a prospective clinical trial
@ast
Late sodium current block for ...... m a prospective clinical trial
@en
type
label
Late sodium current block for ...... m a prospective clinical trial
@ast
Late sodium current block for ...... m a prospective clinical trial
@en
prefLabel
Late sodium current block for ...... m a prospective clinical trial
@ast
Late sodium current block for ...... m a prospective clinical trial
@en
P2093
P2860
P50
P356
P1476
Late sodium current block for ...... m a prospective clinical trial
@en
P2093
C Sanabria
D G Strauss
J Stohlman
P2860
P304
P356
10.1002/CPT.205
P407
P577
2015-11-28T00:00:00Z