TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress. - Wikidata - awgldk - TriplyDB

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.

http://www.wikidata.org/entity/Q33655931

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TRP channel Ca(2+) sparklets: fundamental signals underlying endothelium-dependent hyperpolarization Analysing calcium signalling of cells under high shear flows using discontinuous dielectrophoresis.Pharmacological inhibitors of TRPV4 channels reduce cytokine production, restore endothelial function and increase survival in septic mice Biomechanics of vascular mechanosensation and remodeling Acetylcholine released by endothelial cells facilitates flow-mediated dilatation Heart of the matter: coronary dysfunction in metabolic syndrome.TRPV channels and vascular function H2O2-induced dilation in human coronary arterioles: role of protein kinase G dimerization and large-conductance Ca2+-activated K+ channel activation.Low intravascular pressure activates endothelial cell TRPV4 channels, local Ca2+ events, and IKCa channels, reducing arteriolar tone Role of caveolae in shear stress-mediated endothelium-dependent dilation in coronary arteries.Examination of the role of transient receptor potential vanilloid type 4 in endothelial responses to shear forces.AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension.The primary cilium functions as a mechanical and calcium signaling nexus Functional Tuning of Intrinsic Endothelial Ca2+ Dynamics in Swine Coronary Arteries.TRPV4 mediates flow-induced increases in intracellular Ca in medullary thick ascending limbs.Optimization of a Novel Series of TRPV4 Antagonists with In Vivo Activity in a Model of Pulmonary Edema Determinants of TRPV4 activity following selective activation by small molecule agonist GSK1016790A.Protection of coronary endothelial function during cardiac surgery: potential of targeting endothelial ion channels in cardioprotection Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension.Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force.TRPV4 activation mediates flow-induced nitric oxide production in the rat thick ascending limb.Vascular TRP channels: performing under pressure and going with the flow α1- and α2-adrenergic responsiveness in human skeletal muscle feed arteries: the role of TRPV ion channels in heat-induced sympatholysis Amplification of EDHF-type vasodilatations in TRPC1-deficient mice.Transient receptor potential channel activation and endothelium-dependent dilation in the systemic circulation.An acute rise in intraluminal pressure shifts the mediator of flow-mediated dilation from nitric oxide to hydrogen peroxide in human arterioles.The endothelium: influencing vascular smooth muscle in many ways.Redox signaling via oxidative inactivation of PTEN modulates pressure-dependent myogenic tone in rat middle cerebral arteries The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells Role of TRP channels in the cardiovascular system.Emerging role of the calcium-activated, small conductance, SK3 K+ channel in distal tubule function: regulation by TRPV4 Stochastic model of endothelial TRPV4 calcium sparklets: effect of bursting and cooperativity on EDH.The effect of type-2-diabetes-related vascular endothelial dysfunction on skin physiology and activities of daily living.Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function.Astrocyte contributions to flow/pressure-evoked parenchymal arteriole vasoconstriction Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells.PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells.Regulation of the human coronary microcirculation.Function of transient receptor potential cation channel subfamily V member 4 (TRPV4) as a mechanical transducer in flow-sensitive segments of renal collecting duct system.

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TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.

http://www.wikidata.org/entity/Q33655931

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.

@ast

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.

@en

type

label

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.

@ast

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.

@en

prefLabel

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.

@ast

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.

@en

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AJPHEART.00854.2009

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American Journal of Physiology - Heart and Circulatory Physiology

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TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.

@en

P2093

Aaron H Bubolz

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David A Wilcox

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David D Gutterman

http://www.w3.org/2001/XMLSchema#string

David X Zhang

http://www.w3.org/2001/XMLSchema#string

Juan Fang

http://www.w3.org/2001/XMLSchema#string

Makoto Suzuki

http://www.w3.org/2001/XMLSchema#string

Rongshan Li

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Suelhem A Mendoza

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P2860

OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity

Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress

Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor

Arachidonic acid-induced calcium influx in human platelets. Comparison with the effect of thrombin

TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling

Arterial response to shear stress critically depends on endothelial TRPV4 expression.

Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice.

TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels.

Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives.

Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator

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10.1152/AJPHEART.00854.2009

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