Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force.
about
Transient receptor potential (TRP) channels as drug targets for diseases of the digestive systemFrom mechanosensitivity to inflammatory responses: new players in the pathology of glaucomaTRP channels and analgesiaGenetically targeted magnetic control of the nervous systemTRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye.Mechanically Activated Ion ChannelsDifferential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in MiceFeeling the hidden mechanical forces in lipid bilayer is an original senseGain-of-function mutation in TRPV4 identified in patients with osteonecrosis of the femoral headPolymodal Sensory Integration in Retinal Ganglion Cells.TRPV channels and vascular functionThe puzzle of TRPV4 channelopathies.Functional role for Piezo1 in stretch-evoked Ca²⁺ influx and ATP release in urothelial cell cultures.Increased basal activity is a key determinant in the severity of human skeletal dysplasia caused by TRPV4 mutationsTRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia.Swelling and eicosanoid metabolites differentially gate TRPV4 channels in retinal neurons and gliaMutant TRPV4-mediated toxicity is linked to increased constitutive function in axonal neuropathies.The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cellsL596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel.Stochastic model of endothelial TRPV4 calcium sparklets: effect of bursting and cooperativity on EDH.Expression and characterization of the bacterial mechanosensitive channel MscS in Xenopus laevis oocytesThe core domain as the force sensor of the yeast mechanosensitive TRP channel.Membrane potential and Ca2+ concentration dependence on pressure and vasoactive agents in arterial smooth muscle: A model.PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells.A channelopathy mechanism revealed by direct calmodulin activation of TrpV4.Pressure-dependent regulation of Ca2+ signalling in the vascular endotheliumHuman skeletal dysplasia caused by a constitutive activated transient receptor potential vanilloid 4 (TRPV4) cation channel mutation.Mechanosensitive TRPC1 channels promote calpain proteolysis of talin to regulate spinal axon outgrowth4α-phorbol 12,13-didecanoate activates cultured mouse dorsal root ganglia neurons independently of TRPV4Differential volume regulation and calcium signaling in two ciliary body cell types is subserved by TRPV4 channels.Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli.TRPC5 channels participate in pressure-sensing in aortic baroreceptors.A competing hydrophobic tug on L596 to the membrane core unlatches S4-S5 linker elbow from TRP helix and allows TRPV4 channel to open.Roles of ion transport in control of cell motility.The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements.TRPV4 Stimulation Induced Melatonin Secretion by Increasing Arylalkymine N-acetyltransferase (AANAT) Protein Level.Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes.Yeast luminometric and Xenopus oocyte electrophysiological examinations of the molecular mechanosensitivity of TRPV4.The Role of Mitochondria, Oxidative Stress, and the Radical-binding Protein A1M in Cultured Porcine Retina.Mechanosensitive Ion Channels in Cardiovascular Physiology
P2860
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P2860
Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Wild-type and brachyolmia-caus ...... ond directly to stretch force.
@ast
Wild-type and brachyolmia-caus ...... ond directly to stretch force.
@en
Wild-type and brachyolmia-caus ...... ond directly to stretch force.
@nl
type
label
Wild-type and brachyolmia-caus ...... ond directly to stretch force.
@ast
Wild-type and brachyolmia-caus ...... ond directly to stretch force.
@en
Wild-type and brachyolmia-caus ...... ond directly to stretch force.
@nl
prefLabel
Wild-type and brachyolmia-caus ...... ond directly to stretch force.
@ast
Wild-type and brachyolmia-caus ...... ond directly to stretch force.
@en
Wild-type and brachyolmia-caus ...... ond directly to stretch force.
@nl
P2093
P2860
P356
P1476
Wild-type and brachyolmia-caus ...... ond directly to stretch force.
@en
P2093
Ching Kung
Stephen Loukin
Xinliang Zhou
Yoshiro Saimi
Zhenwei Su
P2860
P304
27176-27181
P356
10.1074/JBC.M110.143370
P407
P577
2010-07-06T00:00:00Z