Frequency and spectrum of mutations produced by a single cis-syn thymine-thymine cyclobutane dimer in a single-stranded vector.
about
Historical overview: searching for replication help in all of the rec placesThe human DINB1 gene encodes the DNA polymerase PolthetaSolution structure of a DNA decamer duplex containing the stable 3' T.G base pair of the pyrimidine(6-4)pyrimidone photoproduct [(6-4) adduct]: implications for the highly specific 3' T --> C transition of the (6-4) adductSolution structure of the DNA decamer duplex containing a 3'-T x T basepair of the cis-syn cyclobutane pyrimidine dimer: implication for the mutagenic property of the cis-syn dimerThe Dewar photoproduct of thymidylyl(3'right-arrow5')- thymidine (Dewar product) exhibits mutagenic behavior in accordance with the"A rule"The mechanisms of UV mutagenesis.The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication.Efficient translesion replication in the absence of Escherichia coli Umu proteins and 3'-5' exonuclease proofreading function.Biological properties of single chemical-DNA adducts: a twenty year perspectiveIn vivo evidence for a recA-independent recombination process in Escherichia coli that permits completion of replication of DNA containing UV damage in both strands.Single d(ApG)/cis-diamminedichloroplatinum(II) adduct-induced mutagenesis in Escherichia coli.Analysis of damage tolerance pathways in Saccharomyces cerevisiae: a requirement for Rev3 DNA polymerase in translesion synthesisIntrinsic polymerase activities of UmuD'(2)C and MucA'(2)B are responsible for their different mutagenic properties during bypass of a T-T cis-syn cyclobutane dimer.Thymine dimer-induced structural changes to the DNA duplex examined with reactive probes (†).Escherichia coli DNA polymerase III can replicate efficiently past a T-T cis-syn cyclobutane dimer if DNA polymerase V and the 3' to 5' exonuclease proofreading function encoded by dnaQ are inactivated.Translesion DNA synthesis and mutagenesis in prokaryotes.Translesion DNA Synthesis.Analysis of CPD ultraviolet lesion bypass in chicken DT40 cells: polymerase η and PCNA ubiquitylation play identical rolesThe relative roles in vivo of Saccharomyces cerevisiae Pol eta, Pol zeta, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site, T-T (6-4) photoadduct and T-T cis-syn cyclobutane dimerMutagenicity of a unique thymine-thymine dimer or thymine-thymine pyrimidine pyrimidone (6-4) photoproduct in mammalian cells.Mutagenesis and more: umuDC and the Escherichia coli SOS response.Detection of thymine [2+2] photodimer repair in DNA: selective reaction of KMnO4Mutagenic and genotoxic effects of DNA adducts formed by the anticancer drug cis-diamminedichloroplatinum(II).Accumulation of the cyclobutane thymine dimer in defined sequences of free and nucleosomal DNA.U-U and T-T cyclobutane dimers have different mutational properties.The Saccharomyces cerevisiae rev6-1 mutation, which inhibits both the lesion bypass and the recombination mode of DNA damage tolerance, is an allele of POL30, encoding proliferating cell nuclear antigen.Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differencesReverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA.Substitution of mucAB or rumAB for umuDC alters the relative frequencies of the two classes of mutations induced by a site-specific T-T cyclobutane dimer and the efficiency of translesion DNA synthesis.Mutagenic properties of the T-C cyclobutane dimer.UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer.The somatic autosomal mutation matrix in cancer genomes.Mutation frequency and spectrum resulting from a single abasic site in a single-stranded vector.Blockage of polymerase-catalyzed DNA chain elongation by chemically modified cytosine residues in templates and the release of blockage for readthrough.Isolation and characterization of novel plasmid-encoded umuC mutantsSingle-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells.The frequency and accuracy of replication past a thymine-thymine cyclobutane dimer are very different in Saccharomyces cerevisiae and Escherichia coli.SOS factors involved in translesion synthesis.SOS-dependent replication past a single trans-syn T-T cyclobutane dimer gives a different mutation spectrum and increased error rate compared with replication past this lesion in uninduced cellsReplication of UV-irradiated DNA in human cell extracts: evidence for mutagenic bypass of pyrimidine dimers.
P2860
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P2860
Frequency and spectrum of mutations produced by a single cis-syn thymine-thymine cyclobutane dimer in a single-stranded vector.
description
1988 nî lūn-bûn
@nan
1988 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Frequency and spectrum of muta ...... r in a single-stranded vector.
@ast
Frequency and spectrum of muta ...... r in a single-stranded vector.
@en
type
label
Frequency and spectrum of muta ...... r in a single-stranded vector.
@ast
Frequency and spectrum of muta ...... r in a single-stranded vector.
@en
prefLabel
Frequency and spectrum of muta ...... r in a single-stranded vector.
@ast
Frequency and spectrum of muta ...... r in a single-stranded vector.
@en
P2093
P2860
P356
P1476
Frequency and spectrum of muta ...... r in a single-stranded vector.
@en
P2093
C W Lawrence
J E LeClerc
R B Christensen
S K Banerjee
P2860
P304
P356
10.1073/PNAS.85.21.8141
P407
P577
1988-11-01T00:00:00Z