Voltage-dependent anion channel 1-based peptides interact with Bcl-2 to prevent antiapoptotic activity.
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Mcl-1 promotes lung cancer cell migration by directly interacting with VDAC to increase mitochondrial Ca2+ uptake and reactive oxygen species generationThe voltage-dependent anion selective channel 1 (VDAC1) topography in the mitochondrial outer membrane as detected in intact cell.Structure-based analysis of VDAC1: N-terminus location, translocation, channel gating and association with anti-apoptotic proteins.The CT20 peptide causes detachment and death of metastatic breast cancer cells by promoting mitochondrial aggregation and cytoskeletal disruption.Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.Mitochondrial VDAC1-based peptides: Attacking oncogenic properties in glioblastoma.The role of glutamate release on voltage-dependent anion channels (VDAC)-mediated apoptosis in an eleven vessel occlusion model in rats.Brain-specific knockdown of miR-29 results in neuronal cell death and ataxia in mice.Reliability of nine programs of topological predictions and their application to integral membrane channel and carrier proteins.Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALSThe Voltage-dependent Anion Channel 1 Mediates Amyloid β Toxicity and Represents a Potential Target for Alzheimer Disease Therapy.The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage-dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca2+ signals to mitochondria.A New Fungal Diterpene Induces VDAC1-dependent Apoptosis in Bax/Bak-deficient Cells.Novel Biomarker Proteins in Chronic Lymphocytic Leukemia: Impact on Diagnosis, Prognosis and Treatment.Mediation of the antiapoptotic activity of Bcl-xL protein upon interaction with VDAC1 proteinVDAC1: from structure to cancer therapy.Olesoxime protects embryonic cortical neurons from camptothecin intoxication by a mechanism distinct from BDNF.Affinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein.An interaction between Bcl-xL and the voltage-dependent anion channel (VDAC) promotes mitochondrial Ca2+ uptake.Small peptides against the mutant SOD1/Bcl-2 toxic mitochondrial complex restore mitochondrial function and cell viability in mutant SOD1-mediated ALSVDAC1-based peptides: novel pro-apoptotic agents and potential therapeutics for B-cell chronic lymphocytic leukemia.News about VDAC1 in Hypoxia.Decreased expression of microRNA-320a promotes proliferation and invasion of non-small cell lung cancer cells by increasing VDAC1 expression.The Mitochondrial Voltage-Dependent Anion Channel 1, Ca2+ Transport, Apoptosis, and Their Regulation.Mitochondrial dysfunction in familial amyotrophic lateral sclerosis.Misfolded SOD1 and ALS: zeroing in on mitochondria.The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond.The functions of voltage-dependent anion channels in plants.S-Nitrosylation in Alzheimer's disease.Mitochondrial channels: ion fluxes and more.The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis.Mitochondrial Ca(2+) Remodeling is a Prime Factor in Oncogenic Behavior.Bcl-2 proteins and calcium signaling: complexity beneath the surface.Ryanodine receptors are targeted by anti-apoptotic Bcl-XL involving its BH4 domain and Lys87 from its BH3 domainModulation of Ca2+ Signaling by Anti-apoptotic B-Cell Lymphoma 2 Proteins at the Endoplasmic Reticulum-Mitochondrial Interface.Adseverin: a novel cisplatin-resistant marker in the human bladder cancer cell line HT1376 identified by quantitative proteomic analysis.p53 and Ca(2+) signaling from the endoplasmic reticulum: partners in anti-cancer therapies.Dominant-negative VDAC1 mutants reveal oligomeric VDAC1 to be the active unit in mitochondria-mediated apoptosis.Voltage-Dependent Anion Channel 1 As an Emerging Drug Target for Novel Anti-Cancer Therapeutics.Mitochondria-Associated Membranes As Networking Platforms and Regulators of Cancer Cell Fate.
P2860
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P2860
Voltage-dependent anion channel 1-based peptides interact with Bcl-2 to prevent antiapoptotic activity.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Voltage-dependent anion channe ...... revent antiapoptotic activity.
@ast
Voltage-dependent anion channe ...... revent antiapoptotic activity.
@en
type
label
Voltage-dependent anion channe ...... revent antiapoptotic activity.
@ast
Voltage-dependent anion channe ...... revent antiapoptotic activity.
@en
prefLabel
Voltage-dependent anion channe ...... revent antiapoptotic activity.
@ast
Voltage-dependent anion channe ...... revent antiapoptotic activity.
@en
P2860
P356
P1476
Voltage-dependent anion channe ...... revent antiapoptotic activity.
@en
P2093
Varda Shoshan-Barmatz
P2860
P304
P356
10.1074/JBC.M109.082990
P407
P577
2009-12-26T00:00:00Z