about
Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatasesProtein kinases and phosphatases in the control of cell fateTherapeutic Implications of Targeting AKT Signaling in MelanomaPancreatic cancer stem cell markers and exosomes - the incentive pushMaximising the potential of AKT inhibitors as anti-cancer treatmentsDifferential regulatory functions of three classes of phosphatidylinositol and phosphoinositide 3-kinases in autophagyEvaluation of MicroRNAs Regulating Anoikis Pathways and Its Therapeutic Potentialα-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutationComputer-aided targeting of the PI3K/Akt/mTOR pathway: toxicity reduction and therapeutic opportunitiesModulation of the Akt pathway reveals a novel link with PERK/eIF2α, which is relevant during hypoxiaPI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen PeroxideRegulation of cardiac hypertrophic signaling by prolyl isomerase Pin1Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female miceMuscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switchingT Cells Deficient in the Tyrosine Phosphatase SHP-1 Resist Suppression by Regulatory T Cells.The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC.Therapeutic ultrasound reverses peripheral ischemia in type 2 diabetic mice through PI3K-Akt-eNOS pathwayPropofol-induced changes in neurotrophic signaling in the developing nervous system in vivoPreclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas.Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.Hyperforin inhibits Akt1 kinase activity and promotes caspase-mediated apoptosis involving Bad and Noxa activation in human myeloid tumor cells.Pivotal role of mTORC2 and involvement of ribosomal protein S6 in cardioprotective signalingShort term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout miceArrest-defective-1 protein (ARD1): tumor suppressor or oncoprotein?B-cell activating factor-receptor specific activation of tumor necrosis factor receptor associated factor 6 and the phosphatidyl inositol 3-kinase pathway in lymphoma B cellsSynergistic signaling of tumor cell invasiveness by hepatocyte growth factor and hypoxia.Genomewide analysis of inherited variation associated with phosphorylation of PI3K/AKT/mTOR signaling proteinsReceptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in β1 integrin-mediated cell survival.Optimal homeostasis necessitates bistable controlA novel functional interplay between Progesterone Receptor-B and PTEN, via AKT, modulates autophagy in breast cancer cells.InterAKTions with FKBPs--mutational and pharmacological exploration.Resveratrol modulates the malignant properties of cutaneous melanoma through changes in the activation and attenuation of the antiapoptotic protooncogenic protein Akt/PKB.Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal.Fibroblast growth factor 1attenuates 6-hydroxydopamine-induced neurotoxicity: an in vitro and in vivo investigation in experimental models of parkinson's disease.Simvastatin induced neurite outgrowth unveils role of cell surface cholesterol and acetyl CoA carboxylase in SH-SY5Y cells.Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibition by 4-hydroxynonenal leads to increased Akt activation in hepatocytes.The beta-arrestin pathway-selective type 1A angiotensin receptor (AT1A) agonist [Sar1,Ile4,Ile8]angiotensin II regulates a robust G protein-independent signaling network.Mdm20 stimulates polyQ aggregation via inhibiting autophagy through Akt-Ser473 phosphorylation.Long-time treatment by low-dose N-acetyl-L-cysteine enhances proinflammatory cytokine expressions in LPS-stimulated macrophages.Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Physiological regulation of Akt activity and stability.
@ast
Physiological regulation of Akt activity and stability.
@en
type
label
Physiological regulation of Akt activity and stability.
@ast
Physiological regulation of Akt activity and stability.
@en
prefLabel
Physiological regulation of Akt activity and stability.
@ast
Physiological regulation of Akt activity and stability.
@en
P2860
P1476
Physiological regulation of Akt activity and stability
@en
P2093
Mien-Chie Hung
P2860
P407
P577
2010-01-01T00:00:00Z