Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.
about
Fucofullerenes as tight ligands of RSL and LecB, two bacterial lectins.Enhanced potency of the metalloprotease inhibitor TAPI-2 by multivalent displaySelection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain.The multivalent effect in glycosidase inhibition: probing the influence of valency, peripheral ligand structure, and topology with cyclodextrin-based iminosugar click clusters.Rescue of functional CFTR channels in cystic fibrosis: a dramatic multivalent effect using iminosugar cluster-based correctors.Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2009-2010.6-Azido hyacinthacine A2 gives a straightforward access to the first multivalent pyrrolizidine architectures.Expanding the library of divalent fucosidase inhibitors with polyamino and triazole-benzyl bridged bispyrrolidines.Binding of single walled carbon nanotube to WT and mutant HIV-1 proteases: analysis of flap dynamics and binding mechanismClick chemistry for drug delivery nanosystems.Glyconanoparticles as multifunctional and multimodal carbohydrate systems.Glyconanotechnology.Multivalent glycoconjugate syntheses and applications using aromatic scaffolds.Bridging lectin binding sites by multivalent carbohydrates.Therapeutic potential of carbohydrate-based polymeric and nanoparticle systems.Fullerene sugar balls: a new class of biologically active fullerene derivatives.The multivalent effect in glycosidase inhibition: a new, rapidly emerging topic in glycoscience.Multivalent inhibitors for carbohydrate-processing enzymes: beyond the "lock-and-key" concept.Synthesis of highly functionalized C60 fullerene derivatives and their applications in material and life sciences.Emerging trends in enzyme inhibition by multivalent nanoconstructs.Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition.Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels.Synthesis of the first examples of iminosugar clusters based on cyclopeptoid coresLow-generation dendrimers with a calixarene core and based on a chiral C(2)-symmetric pyrrolidine as iminosugar mimics.Design, synthesis and photochemical properties of the first examples of iminosugar clusters based on fluorescent cores.Soccer goes BOXing: synthetic access to novel [6:0] hexakis[(bisoxazolinyl)methano]fullerenes.Exploring architectures displaying multimeric presentations of a trihydroxypiperidine iminosugar.Synthesis of dodecavalent fullerene-based glycoclusters and evaluation of their binding properties towards a bacterial lectin.Dynamic constitutional electrodes toward functional fullerene wires.The inhibition of liposaccharide heptosyltransferase WaaC with multivalent glycosylated fullerenes: a new mode of glycosyltransferase inhibition.Fullerene-sp2-iminosugar balls as multimodal ligands for lectins and glycosidases: a mechanistic hypothesis for the inhibitory multivalent effect.A systematic investigation of iminosugar click clusters as pharmacological chaperones for the treatment of Gaucher disease.Polycationic pillar[5]arene derivatives: interaction with DNA and biological applications.The Impact of Heteromultivalency in Lectin Recognition and Glycosidase Inhibition: An Integrated Mechanistic Study.Multimeric xanthates as carbonic anhydrase inhibitors.Exploring carbonic anhydrase inhibition with multimeric coumarins displayed on a fullerene scaffold.Self-organisation of dodeca-dendronized fullerene into supramolecular discs and helical columns containing a nanowire-like core.Fullerene hexa-adduct scaffolding for the construction of giant molecules.Mechanistic Insight into Heptosyltransferase Inhibition by using Kdo Multivalent Glycoclusters.Pyruvate-Kinase-Coupled Glycosyltransferase Assays: Limitations, Struggles and Problem Resolution.
P2860
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P2860
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.
@ast
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.
@en
type
label
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.
@ast
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.
@en
prefLabel
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.
@ast
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.
@en
P2093
P50
P356
P1476
Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect
@en
P2093
Camille Decroocq
Damien Hazelard
Julien Iehl
Philippe Compain
Teresa Mena Barragán
P304
P356
10.1002/ANIE.201002802
P407
P577
2010-08-01T00:00:00Z