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Molecular basis for beta-glucosidase inhibition by ring-modified calystegine analogues6-Amino-6-deoxy-5,6-di-N-(N'-octyliminomethylidene)nojirimycin: synthesis, biological evaluation, and crystal structure in complex with acid beta-glucosidaseGlycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoringCyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analoguesInfluence of the macroring size on the self-association thermodynamics of cyclodextrins with a double-linked naphthalene at the secondary face.Castanospermine-trehazolin hybrids: a new family of glycomimetics with tuneable glycosidase inhibitory properties.Synthesis of glycosyl(thio)ureido sugars via carbodiimides and their conformational behaviour in water.Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.Neuronopathic Gaucher's disease: induced pluripotent stem cells for disease modelling and testing chaperone activity of small compounds.The multivalent effect in glycosidase inhibition: probing the influence of valency, peripheral ligand structure, and topology with cyclodextrin-based iminosugar click clusters.Effects of inulin and di-D-fructose dianhydride-enriched caramels on intestinal microbiota composition and performance of broiler chickens.New castanospermine glycoside analogues inhibit breast cancer cell proliferation and induce apoptosis without affecting normal cellsCyclodextrin-based facial amphiphiles: assessing the impact of the hydrophilic-lipophilic balance in the self-assembly, DNA complexation and gene delivery capabilities.(Pseudo)amide-linked oligosaccharide mimetics: molecular recognition and supramolecular properties.Cyclodextrin-based gene delivery systems.Pharmacological chaperone therapy for Gaucher disease: a patent review.Multivalency in heterogeneous glycoenvironments: hetero-glycoclusters, -glycopolymers and -glycoassemblies.Cyclodextrin-based multivalent glycodisplays: covalent and supramolecular conjugates to assess carbohydrate-protein interactions.sp2-Iminosugar O-, S-, and N-glycosides as conformational mimics of α-linked disaccharides; implications for glycosidase inhibition.Probing secondary carbohydrate-protein interactions with highly dense cyclodextrin-centered heteroglycoclusters: the heterocluster effect.Probing carbohydrate-lectin recognition in heterogeneous environments with monodisperse cyclodextrin-based glycoclusters.Optimizing saccharide-directed molecular delivery to biological receptors: design, synthesis, and biological evaluation of glycodendrimer-cyclodextrin conjugates.A general entry to linear, dendritic and branched thiourea-linked glycooligomers as new motifs for phosphate ester recognition in water.Cyclotrehalins: cyclooligosaccharide receptors featuring a hydrophobic cavity.Targeted gene delivery by new folate-polycationic amphiphilic cyclodextrin-DNA nanocomplexes in vitro and in vivo.Bicyclic derivatives of L-idonojirimycin as pharmacological chaperones for neuronopathic forms of Gaucher disease.Polycationic amphiphilic cyclodextrins as gene vectors: effect of the macrocyclic ring size on the DNA complexing and delivery properties.Polycationic amphiphilic cyclodextrin-based nanoparticles for therapeutic gene delivery.Symmetry complementarity-guided design of anthrax toxin inhibitors based on β-cyclodextrin: Synthesis and relative activities of face-selective functionalized polycationic clusters.A Fluorescent sp2-iminosugar with pharmacological chaperone activity for gaucher disease: synthesis and intracellular distribution studies.Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition.Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral alpha-glucosidase inhibitory activity as antitumour agents.Polycationic amphiphilic cyclodextrins for gene delivery: synthesis and effect of structural modifications on plasmid DNA complex stability, cytotoxicity, and gene expression.Preorganized, macromolecular, gene-delivery systems.Structural basis of pharmacological chaperoning for human β-galactosidase.Synthesis and evaluation of sulfamide-type indolizidines as glycosidase inhibitors.A bicyclic 1-deoxygalactonojirimycin derivative as a novel pharmacological chaperone for GM1 gangliosidosis.Fluorescent-tagged sp2-iminosugars with potent β-glucosidase inhibitory activity.Di-D-fructose dianhydride-enriched caramels: effect on colon microbiota, inflammation, and tissue damage in trinitrobenzenesulfonic acid-induced colitic rats.Insights in cellular uptake mechanisms of pDNA-polycationic amphiphilic cyclodextrin nanoparticles (CDplexes).
P50
Q27652390-10AEB124-1EA3-4E38-B72E-7588144D3F5EQ27655457-4F612E3F-D70A-425B-9670-BD66913EB23DQ27655995-8C895013-2384-4FCB-BB32-CFAC899C3918Q27667205-DEFA91FF-236D-4D5F-8F92-5F51886B781FQ30617271-CBAFDFDE-9029-480A-AC03-656E4D041235Q30704789-E125ACDB-8A49-418E-80ED-D23223B6FAF2Q31791623-EC7DB4D2-A06E-4B52-8B35-4097BA252FE4Q33684846-BD32E33B-1C53-47AB-83FE-87B4B7AB1ADFQ34464236-C960C472-6C56-43A6-A572-6F23E7B089A2Q34981135-92C1CE90-7BCD-4E76-9C82-1AE75DE2D642Q34982199-4CD8B334-DE9B-4AA8-8264-8D3D8BCA6D6AQ35016962-D1230CD8-5745-4525-B2CA-F6E2FCE98DB0Q36158967-3DF2CF37-E011-43AB-9D58-98B9755C4C6CQ37756536-956DC878-AF1A-4C91-BCB4-9879EA60B1ACQ37806096-C6575F37-C57E-49D1-8BE1-CC6A07A0E7D8Q37860332-34634D24-8072-4E91-8384-52DE93B21CFAQ38036582-540E0AB5-5456-4363-B7C1-F3185DB095BDQ38076027-7D96A241-598B-4715-B04C-8CEE5CDAF7CBQ38324679-A378B7BD-5329-4864-8568-65464EEE1462Q38325650-DF577726-0480-4ED7-9831-2225EFADA457Q38329315-385F13BB-3182-4FC2-8413-568A39D0252EQ38337627-27253CC6-14ED-4417-A44C-802B182A9471Q38345692-12AEB667-6B6E-4D70-8FFA-87940F54E4C1Q38362172-85A1789F-0583-4428-93FE-3F67025D431DQ39133271-5FCD8948-54F2-42AF-A94D-3FBAA359A83FQ39162679-FD004078-AAF1-4CF5-910E-0764FE5FCB47Q39325207-26CF2F41-44F6-48B3-AA6D-857F56482B8FQ39436385-8A23963D-F8A7-4533-8573-38F6C794A01CQ39622585-A3DF5772-A33F-4AB5-AFD9-676AC93F7112Q39633727-1B1FB767-0672-488B-9A8B-F969D3AD8FEEQ39635191-D615FC64-E7AA-40C4-AAAA-41A6518B5D46Q39692460-86E82082-221E-43FB-9E3A-7CF229B4A17FQ39786784-1B73F94E-3338-433E-A835-ED3D1D1587E8Q39868196-DC029840-0F7E-4FCB-9430-06CF29369384Q39885525-E72CB923-3A2D-45E7-A806-8A039155942CQ39990965-6F990141-7FE3-44F8-9F9E-79EB45231A23Q41574484-74184E65-A30E-4207-9621-FC7CA1110727Q42871238-38F4A101-D66E-4270-A2CF-05270DD86A31Q43084156-0EFB21D2-4C1B-4E13-9A41-688654382BD3Q43185770-3A6FE0BF-A0A7-4D45-A8DE-609671877FFA
P50
description
hulumtuese
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researcher
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wetenschapper
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հետազոտող
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name
Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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type
label
Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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altLabel
Carmen Ortiz Mellet
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Maria C. Ortiz Mellet
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Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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Carmen Ortiz Mellet
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P1053
C-7993-2011
P106
P1153
24406095000
6603444098
P21
P31
P3829
P496
0000-0002-7676-7721