Screening therapeutic EMT blocking agents in a three-dimensional microenvironment - Wikidata - awgldk - TriplyDB

Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

http://www.wikidata.org/entity/Q33689694

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Targeting Epithelial-Mesenchymal Transition (EMT) to Overcome Drug Resistance in Cancer Microscale screening systems for 3D cellular microenvironments: platforms, advances, and challenges A Novel High-Throughput 3D Screening System for EMT Inhibitors: A Pilot Screening Discovered the EMT Inhibitory Activity of CDK2 Inhibitor SU9516 Organs-on-chips at the frontiers of drug discovery An ex vivo model for anti-angiogenic drug testing on intact microvascular networks Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment Three dimensional microfluidic cell arrays for ex vivo drug screening with mimicked vascular flow.Microfluidic co-cultures of retinal pigment epithelial cells and vascular endothelial cells to investigate choroidal angiogenesis.Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment.A Facile Method to Probe the Vascular Permeability of Nanoparticles in Nanomedicine Applications.Rapid prototyping of concave microwells for the formation of 3D multicellular cancer aggregates for drug screening.Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array.Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.Redox processes inform multivariate transdifferentiation trajectories associated with TGFβ-induced epithelial-mesenchymal transition Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.Effect of vascular formed endothelial cell network on the invasive capacity of melanoma using the in vitro 3D co-culture patterning model.Printing cancer cells into intact microvascular networks: a model for investigating cancer cell dynamics during angiogenesis.Contact-dependent carcinoma aggregate dispersion by M2a macrophages via ICAM-1 and β2 integrin interactions.Identification of drugs as single agents or in combination to prevent carcinoma dissemination in a microfluidic 3D environment Engineering a 3D microfluidic culture platform for tumor-treating field application.Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma.A new dimension in drug discovery: reversing epithelial-mesenchymal transition (EMT).Cancer: A disease at the crossroads of trade-offs.Integration concepts for multi-organ chips: how to maintain flexibility?!Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.Multicellular tumor invasion and plasticity in biomimetic materials.Bridging the gap: microfluidic devices for short and long distance cell-cell communication.A 3-D cell culture system to study epithelia functions using microcarriers Microfluidic models for adoptive cell-mediated cancer immunotherapies PTEN deletion potentiates invasion of colorectal cancer spheroidal cells through 3D Matrigel.A spatiotemporally defined in vitro microenvironment for controllable signal delivery and drug screening.Validating antimetastatic effects of natural products in an engineered microfluidic platform mimicking tumor microenvironment.The EMT spectrum and therapeutic opportunities.Organ-on-a-chip devices advance to market.Tracking the tumor invasion front using long-term fluidic tumoroid culture Microfluidics for Antibiotic Susceptibility and Toxicity Testing Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling.Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.A tuneable microfluidic system for long duration chemotaxis experiments in a 3D collagen matrix.Controlling Differentiation of Stem Cells for Developing Personalized Organ-on-Chip Platforms.

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P2860

Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

http://www.wikidata.org/entity/Q33689694

description

2013 nî lūn-bûn

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2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի փետրվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

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Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

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type

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Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

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Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

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prefLabel

Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

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Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

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Integrative Biology

P1476

Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

@en

P2093

Amir R Aref

http://www.w3.org/2001/XMLSchema#string

Ioannis K Zervantonakis

http://www.w3.org/2001/XMLSchema#string

Jean Paul Thiery

http://www.w3.org/2001/XMLSchema#string

Jing Bai

http://www.w3.org/2001/XMLSchema#string

Kian-Ngiap Chua

http://www.w3.org/2001/XMLSchema#string

Roger D Kamm

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Ruby Yun-Ju Huang

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Ting-Yuan Tu

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Wei Sun

http://www.w3.org/2001/XMLSchema#string

Weimiao Yu

http://www.w3.org/2001/XMLSchema#string

P2860

Hallmarks of Cancer: The Next Generation

2D protrusion but not motility predicts growth factor-induced cancer cell migration in 3D collagen

TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT)

Epithelial-mesenchymal transitions in tumour progression

Epithelial-mesenchymal transitions in development and disease

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

Degrading devices: invadosomes in proteolytic cell invasion

Identification of selective inhibitors of cancer stem cells by high-throughput screening

Ensemble analysis of angiogenic growth in three-dimensional microfluidic cell cultures

Microenvironmental regulation of metastasis

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381-389

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10.1039/C2IB20209C

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2

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5

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2013-02-01T00:00:00Z

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233745467

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23172153

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4039387

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