Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth. - Wikidata - awgldk - TriplyDB

Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.

Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.

http://www.wikidata.org/entity/Q35145319

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Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening Apigenin inhibits TNFα/IL-1α-induced CCL2 release through IKBK-epsilon signaling in MDA-MB-231 human breast cancer cells Detection of IKKε by immunohistochemistry in primary breast cancer: association with EGFR expression and absence of lymph node metastasis.Challenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast Cancer New Insights in the Cytogenetic Practice: Karyotypic Chaos, Non-Clonal Chromosomal Alterations and Chromosomal Instability in Human Cancer and Therapy Response Cytoplasmic Localization of Proline, Glutamic Acid, Leucine-rich Protein 1 (PELP1) Induces Breast Epithelial Cell Migration through Up-regulation of Inhibitor of κB Kinase ϵ and Inflammatory Cross-talk with Macrophages.RelA-Induced Interferon Response Negatively Regulates Proliferation Redox-modulating agents target NOX2-dependent IKKε oncogenic kinase expression and proliferation in human breast cancer cell lines Multivariate models from RNA-Seq SNVs yield candidate molecular targets for biomarker discovery: SNV-DA IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.Sex Difference of Egfr Expression and Molecular Pathway in the Liver: Impact on Drug Design and Cancer Treatments?Rap1-mediated nuclear factor-kappaB (NF-κB) activity regulates the paracrine capacity of mesenchymal stem cells in heart repair following infarction Upregulation of microRNA-181b inhibits CCL18-induced breast cancer cell metastasis and invasion via the NF-κB signaling pathway.Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence.Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity.IKBKE Is Required during KRAS-Induced Pancreatic Tumorigenesis.Triple negative breast cancer: the kiss of death.Effective personalized therapy for breast cancer based on predictions of cell signaling pathway activation from gene expression analysis.The intersection of RB tumor suppressor function, stem cells, metabolism and inflammation.Autophagy Inhibition Dysregulates TBK1 Signaling and Promotes Pancreatic Inflammation.Amlexanox, a selective inhibitor of IKBKE, generates anti-tumoral effects by disrupting the Hippo pathway in human glioblastoma cell lines IKBKE Is a Substrate of EGFR and a Therapeutic Target in Non-Small Cell Lung Cancer with Activating Mutations of EGFR.RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer.IκB-kinase-ε in the tumor microenvironment is essential for the progression of gastric cancer.The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis.Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer.Phenylmethimazole and a thiazole derivative of phenylmethimazole inhibit IL-6 expression by triple negative breast cancer cells.Unlocking the NF-κB Conundrum: Embracing Complexity to Achieve Specificity.RANTES and IL-6 cooperate in inducing a more aggressive phenotype in breast cancer cells.IΚΚε cooperates with either MEK or non-canonical NF-kB driving growth of triple-negative breast cancer cells in different contexts.Roles for the IKK-Related Kinases TBK1 and IKKε in Cancer Proteasome inhibition induces IKK-dependent interleukin-8 expression in triple negative breast cancer cells: Opportunity for combination therapy

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Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.

http://www.wikidata.org/entity/Q35145319

description

2014 nî lūn-bûn

@nan

2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.

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Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.

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Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.

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Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.

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Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth

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Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.

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Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.

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Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth.

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Amir R Aref

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David A Barbie

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Gabriela Alexe

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Jill P Mesirov

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John Herndon

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Michaela Bowden

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Pablo Tamayo

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Shunqiang Li

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Thanh U Barbie

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P2860

IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

Rantes activates Jak2 and Jak3 to regulate engagement of multiple signaling pathways in T cells

Emerging roles for the non-canonical IKKs in cancer

Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts

Comprehensive molecular portraits of human breast tumours

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

Triggering the interferon antiviral response through an IKK-related pathway

Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity

Triple-negative breast cancer: an unmet medical need

CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection

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