Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.
about
The role of T-cell receptor recognition of peptide:MHC complexes in the formation and activity of Foxp3⁺ regulatory T cells.How specificity for self-peptides shapes the development and function of regulatory T cells.B7/CD28 in central tolerance: costimulation promotes maturation of regulatory T cell precursors and prevents their clonal deletion.Models of self-peptide sampling by developing T cells identify candidate mechanisms of thymic selection.CD4⁺CD25⁺Foxp3⁺ regulatory T cell formation requires more specific recognition of a self-peptide than thymocyte deletionTheories and quantification of thymic selection.Regulatory T-cell differentiation versus clonal deletion of autoreactive thymocytes.Self-tolerance in multiple sclerosis.Strength of TCR signal from self-peptide modulates autoreactive thymocyte deletion and Foxp3(+) Treg-cell formation.How antigen specificity directs regulatory T-cell function: self, foreign and engineered specificity.Distinct modes of antigen presentation promote the formation, differentiation, and activity of foxp3+ regulatory T cells in vivo.Flow cytometric profiling of mature and developing regulatory T cells in the thymus.The amount of self-antigen determines the effector function of murine T cells escaping negative selection.
P2860
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P2860
Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.
@ast
Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.
@en
type
label
Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.
@ast
Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.
@en
prefLabel
Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.
@ast
Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.
@en
P2093
P2860
P356
P1476
Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.
@en
P2093
Alissa Basehoar
Andrew J Caton
Cristina Cozzo Picca
Laura Panarey
Malinda Aitken
Soyoung Oh
P2860
P304
P356
10.1002/EJI.200939709
P407
P577
2009-12-01T00:00:00Z