Intraclonal competition limits the fate determination of regulatory T cells in the thymus. - Wikidata - awgldk - TriplyDB

Intraclonal competition limits the fate determination of regulatory T cells in the thymus.

Intraclonal competition limits the fate determination of regulatory T cells in the thymus.

http://www.wikidata.org/entity/Q34607464

about

T cell receptor signalling in the control of regulatory T cell differentiation and function Cellular and molecular determinants for the development of natural and induced regulatory T cells Homeostasis and function of regulatory T cells (Tregs) in vivo: lessons from TCR-transgenic Tregs To affinity and beyond: harnessing the T cell receptor for cancer immunotherapy Organ-specific and memory treg cells: specificity, development, function, and maintenance Nature and nurture in Foxp3(+) regulatory T cell development, stability, and function Development of thymic Foxp3(+) regulatory T cells: TGF-β matters Continuous activation of the CD122/STAT-5 signaling pathway during selection of antigen-specific regulatory T cells in the murine thymus Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)Regulatory T cells: mechanisms of differentiation and function Once a Treg, always a Treg?The role of T-cell receptor recognition of peptide:MHC complexes in the formation and activity of Foxp3⁺ regulatory T cells.Thymocyte deletion can bias Treg formation toward low-abundance self-peptide.Induced Regulatory T Cells Superimpose Their Suppressive Capacity with Effector T Cells in Lymph Nodes via Antigen-Specific S1p1-Dependent Egress Blockage.CD28 facilitates the generation of Foxp3(-) cytokine responsive regulatory T cell precursors.T cell receptor CDR3 sequence but not recognition characteristics distinguish autoreactive effector and Foxp3(+) regulatory T cells.Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development.Extra-thymically induced regulatory T cells: do they have potential in disease prevention?Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis.Shaping the repertoire of tumor-infiltrating effector and regulatory T cells.Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells Control of Th2-mediated inflammation by regulatory T cells.The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2.Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints.Both positive and negative effects on immune responses by expression of a second class II MHC molecule.Regulatory T cells and Foxp3 Both retention and recirculation contribute to long-lived regulatory T-cell accumulation in the thymus.The same self-peptide selects conventional and regulatory CD4⁺ T cells with identical antigen receptors.Elevated T cell receptor signaling identifies a thymic precursor to the TCRαβ(+)CD4(-)CD8β(-) intraepithelial lymphocyte lineage.Novel process of intrathymic tumor-immune tolerance through CCR2-mediated recruitment of Sirpα+ dendritic cells: a murine model.Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals How specificity for self-peptides shapes the development and function of regulatory T cells.Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns.Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development.Foxo: in command of T lymphocyte homeostasis and tolerance.Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway Control of regulatory T cell lineage commitment and maintenance.Becoming self-aware: the thymic education of regulatory T cells.γδ T cells acquire effector fates in the thymus and differentiate into cytokine-producing effectors in a Listeria model of infection independently of CD28 costimulation.Models of self-peptide sampling by developing T cells identify candidate mechanisms of thymic selection.

P2860

Q26749508-17267CC1-E0AF-4AF8-9616-7885AF603015 Q26853475-53EF101E-AA6D-438B-93C6-66AAC90904BF Q26853599-BDD84D7C-BEE1-4232-B1F1-4CFF5D154498 Q27008423-5B571547-239E-44B7-B24C-57CD9FA2B637 Q27010198-0AF8225E-D1EF-4CA1-9FD5-584F57D7CC6C Q27014799-FAFAE2E7-116C-4874-8FF1-C044EC3C450A Q28080745-A5156C7E-750B-46F1-9C48-63A79F967684 Q28740737-82732078-B9AD-480D-9F4F-252D1DECC955 Q29391777-9E07E40B-C87C-4CE5-B494-7657A9924145 Q29620731-F95FEEDD-7753-4846-AAA1-7FAD7BEF6FB5 Q33561651-880A9950-A6A1-44E3-876A-1FBF7FCB0236 Q33666979-6AB1EB22-BF06-4D08-AF97-EE8901A28155 Q33692483-633188B3-3CF2-4377-885F-0B12C42FD37A Q33770196-DEFA7585-41F3-461A-A652-5A2382B0B132 Q33867240-6BE8654F-67FF-410D-8F2A-A57D84F45470 Q33886349-994899EC-684C-42AD-AC6D-54151750D9E4 Q33892077-1CAB1E98-8CF6-4DFC-AF1B-48725C8614BA Q33949282-86B2FC1F-3B55-40C3-97AF-143A5683FFF7 Q33979892-F5F3B43E-CC57-4D05-ADD8-A6B44D6F2782 Q34003592-02B5B9FC-0A75-4EA4-9DC9-E70B9F4B825D Q34026357-E25BDF0B-B38B-4366-B03B-6B6BC1E673F3 Q34033388-4D66425A-0B5B-40FD-BA75-15E41B4064E4 Q34071164-604FB807-B378-4D3A-B7C1-927A6C6ED320 Q34096519-F13873C6-A9F5-44DD-96A5-12A3891998EA Q34146648-B6ACD644-823E-45AD-A930-427349BE173B Q34177949-971F150A-F9FA-44E5-AC26-48BC0F959DB2 Q34253182-8D1554D2-1594-4BE4-AF24-3046332DE725 Q34284280-C336AA26-1CA9-4D3F-90BD-45E6FFD989D9 Q34301124-E820B04C-5CE2-475B-83EC-34F69EC4DA5B Q34345734-D2C2E731-B94C-4D02-9C3E-6B89EA89DB7B Q34349363-153228FE-8A17-4F46-AA09-D7E6ADAA6956 Q34378731-C8F68D2F-84D6-48F6-96A4-B427A6A05D84 Q34507271-ED26869A-F253-414D-84DB-5DB693539577 Q34617728-2BD20CC5-F878-4CF1-BDA3-11BA7EDEC155 Q34645402-61A1B86D-DC6E-4AF6-AADA-BCE2014F868B Q34649977-65616D70-1945-4D61-B74E-007FF58A9386 Q34658594-F6F86A40-DE8F-4DAE-B9E7-18E16BF8B0DB Q34700458-EC5FB2B7-06EA-4280-8BC0-F632D704406A Q34721076-C6C92048-3174-4CBA-966F-E5524663A60A Q34916448-33A0DAD8-AAA3-48EE-A2DF-C33094AE7027

P2860

Intraclonal competition limits the fate determination of regulatory T cells in the thymus.

http://www.wikidata.org/entity/Q34607464

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Intraclonal competition limits ...... ulatory T cells in the thymus.

@ast

Intraclonal competition limits ...... ulatory T cells in the thymus.

@en

Intraclonal competition limits ...... ulatory T cells in the thymus.

@nl

type

label

Intraclonal competition limits ...... ulatory T cells in the thymus.

@ast

Intraclonal competition limits ...... ulatory T cells in the thymus.

@en

Intraclonal competition limits ...... ulatory T cells in the thymus.

@nl

prefLabel

Intraclonal competition limits ...... ulatory T cells in the thymus.

@ast

Intraclonal competition limits ...... ulatory T cells in the thymus.

@en

Intraclonal competition limits ...... ulatory T cells in the thymus.

@nl

P1433

Q34607464-01AFC7F0-FF08-4F71-89FC-7CC9F827C94A

P1476

Q34607464-AFF7A64E-519C-4AA6-B375-191A8B99AC59

P2093

Q34607464-33A2CDF7-FAB2-49AA-95A6-DCB727E00A7B

Q34607464-497D2F8C-9D28-4CFA-8748-9224B5AF8CFE

Q34607464-58788842-BF8D-4962-B0CA-CE130A0C9797

Q34607464-A5357CAA-E4DE-478A-B8C1-46BC87AAB632

Q34607464-B700D80F-CED6-4345-895B-70ABB00A90D2

Q34607464-EE68964B-1A13-4FE8-988F-96FB4FE28EE0

P2860

Q34607464-03D5E6D1-654C-46BB-93D0-F517B5704A9B

Q34607464-06DE7D5C-2BC0-4AF7-829D-00F02FA44AA9

Q34607464-074ABAEE-0F5D-4FA8-8089-FED5D78C2AC1

Q34607464-0CA1A059-7BCE-4A98-B7D7-42013D8526AB

Q34607464-0E8B6C03-C359-4BCE-93B3-413F6FD4A537

Q34607464-0FD95EE3-F7E4-4E53-A091-D140F2C192B3

Q34607464-123CF299-7391-4AF1-9E86-4D627368D57C

Q34607464-15B3A5F9-0BE6-4402-880A-90147F1D79CE

Q34607464-198CC0B2-DDAC-47C2-A8ED-8CD19E8E55BA

Q34607464-1A7DDE95-A14E-4A5B-B949-71F281518C62

P304

Q34607464-F4A2C0F9-CB58-4F6E-9EDE-7D301A3AD54C

P31

Q34607464-70C7051E-0764-46AD-9E37-833AAD38A35D

P356

Q34607464-019C9EA8-DBAB-446E-A6D9-785107743AF6

P407

Q34607464-064758FE-977A-485E-BC3E-6B3146C90DDF

P433

Q34607464-1E851525-ECE9-489B-A390-33E13C192526

P478

Q34607464-7CE30699-ED84-4BFF-A4DE-A28E92324DB8

P50

Q34607464-389A774B-AF6B-42E5-A6D4-569F3585BE32

Q34607464-9B2AB398-E76C-41CD-8917-AAF26DDC7B0C

P577

Q34607464-FD9854B5-4383-4BB8-87D6-3A3AF76DF1A2

P5875

Q34607464-E0BFEAD6-602C-4C6B-A35D-3C39836D9B37

P698

Q34607464-5D319F9E-AC55-4DA1-8D05-4AD9BBF932FA

P932

Q34607464-E8FFF251-B00E-4843-8310-F4CA66FAA165

P356

P1433

Nature Immunology

P1476

Intraclonal competition limits ...... gulatory T cells in the thymus

@en

P2093

Alexander Y Rudensky

http://www.w3.org/2001/XMLSchema#string

Chyi-Song Hsieh

http://www.w3.org/2001/XMLSchema#string

Jingqin Luo

http://www.w3.org/2001/XMLSchema#string

Katherine Forbush

http://www.w3.org/2001/XMLSchema#string

Stephanie K Lathrop

http://www.w3.org/2001/XMLSchema#string

Yuqiong Liang

http://www.w3.org/2001/XMLSchema#string

P2860

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

Regulatory T cells and immune tolerance

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion.

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice.

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice.

Competition for self ligands restrains homeostatic proliferation of naive CD4 T cells

Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance.

In vivo instruction of suppressor commitment in naive T cells

P304

610-617

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NI.1739

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

10

http://www.w3.org/2001/XMLSchema#string

P50

Chan-Wang Joaquim Lio

Jhoanne Bautista

P577

2009-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

24416047

http://www.w3.org/2001/XMLSchema#string

P698

19430476

http://www.w3.org/2001/XMLSchema#string

P932

2756247

http://www.w3.org/2001/XMLSchema#string