A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.
about
Targeting DNA Replication Stress for Cancer TherapyThe Impact of Hedgehog Signaling Pathway on DNA Repair Mechanisms in Human CancerBRCA1, a 'complex' protein involved in the maintenance of genomic stabilityThe cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration.Integrating Multi-omics Data to Dissect Mechanisms of DNA repair Dysregulation in Breast CancerPoly(ADP-ribosylation) is present in murine sciatic nerve fibers and is altered in a Charcot-Marie-Tooth-1E neurodegenerative model.Complex-based analysis of dysregulated cellular processes in cancer.The actin depolymerizing factor (ADF)/cofilin signaling pathway and DNA damage responses in cancerCrosstalk between translesion synthesis, Fanconi anemia network, and homologous recombination repair pathways in interstrand DNA crosslink repair and development of chemoresistanceA polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients.RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins.GC-Rich Extracellular DNA Induces Oxidative Stress, Double-Strand DNA Breaks, and DNA Damage Response in Human Adipose-Derived Mesenchymal Stem CellsPit-1 inhibits BRCA1 and sensitizes human breast tumors to cisplatin and vitamin D treatment.Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer.ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes.Ionizing radiation-induced DNA injury and damage detection in patients with breast cancerExpression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon CancerMethods for protein complex prediction and their contributions towards understanding the organisation, function and dynamics of complexes.Personalised pathway analysis reveals association between DNA repair pathway dysregulation and chromosomal instability in sporadic breast cancer.Use of the HPRT gene to study nuclease-induced DNA double-strand break repair.ELAS1-mediated inhibition of the cyclin G1-B'γ interaction promotes cancer cell apoptosis via stabilization and activation of p53.Cdk5 links with DNA damage response and cancer.Mechanisms of DNA damage, repair, and mutagenesis.FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids.Environmental Stress Induces Trinucleotide Repeat Mutagenesis in Human Cells by Alt-Nonhomologous End Joining Repair.Exploiting DNA repair defects for novel cancer therapies.Challenges for Super-Resolution Localization Microscopy and Biomolecular Fluorescent Nano-Probing in Cancer Research.ELAS1 induces apoptotic death in adenocarcinoma DU145 and squamous-cell carcinoma SAS cancer cells, but not in normal KD cells.Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair.Androgen receptor inhibitor-induced "BRCAness" and PARP inhibition are synthetically lethal for castration-resistant prostate cancer.New therapeutic strategies to treat human cancers expressing mutant p53 proteins.Understanding the functional impact of copy number alterations in breast cancer using a network modeling approach
P2860
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P2860
A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A fine-scale dissection of the ...... ons for breast cancer therapy.
@ast
A fine-scale dissection of the ...... ons for breast cancer therapy.
@en
type
label
A fine-scale dissection of the ...... ons for breast cancer therapy.
@ast
A fine-scale dissection of the ...... ons for breast cancer therapy.
@en
prefLabel
A fine-scale dissection of the ...... ons for breast cancer therapy.
@ast
A fine-scale dissection of the ...... ons for breast cancer therapy.
@en
P2093
P2860
P50
P356
P1476
A fine-scale dissection of the ...... ons for breast cancer therapy.
@en
P2093
Kim-Anh Lê Cao
Kum Kum Khanna
P2860
P304
P356
10.1093/NAR/GKU284
P407
P5008
P577
2014-05-03T00:00:00Z
2014-06-01T00:00:00Z