Thermodynamics-based models of transcriptional regulation by enhancers: the roles of synergistic activation, cooperative binding and short-range repression.
about
Homotypic clusters of transcription factor binding sites: A model system for understanding the physical mechanics of gene expressionPredicting Ancestral Segmentation Phenotypes from Drosophila to Anopheles Using In Silico EvolutionQuantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila developmentVersatility of cooperative transcriptional activation: a thermodynamical modeling analysis for greater-than-additive and less-than-additive effectsA linear framework for time-scale separation in nonlinear biochemical systemsWhat does it take to evolve an enhancer? A simulation-based study of factors influencing the emergence of combinatorial regulationThe appeasement of Doug: a synthetic approach to enhancer biology.Molecular mechanisms of system responses to novel stimuli are predictable from public dataPredicting expression: the complementary power of histone modification and transcription factor binding data.Incorporating chromatin accessibility data into sequence-to-expression modelingIntegrating motif, DNA accessibility and gene expression data to build regulatory maps in an organismNetwork component analysis provides quantitative insights on an Arabidopsis transcription factor-gene regulatory networkA conserved developmental patterning network produces quantitatively different output in multiple species of Drosophila.Decoding ChIP-seq with a double-binding signal refines binding peaks to single-nucleotides and predicts cooperative interaction.Modeling of gap gene expression in Drosophila Kruppel mutantsEvidence for deep regulatory similarities in early developmental programs across highly diverged insectsThe underlying molecular and network level mechanisms in the evolution of robustness in gene regulatory networks.Rearrangements of 2.5 kilobases of noncoding DNA from the Drosophila even-skipped locus define predictive rules of genomic cis-regulatory logicA framework for modelling gene regulation which accommodates non-equilibrium mechanisms.Chromatin-specific regulation of mammalian rDNA transcription by clustered TTF-I binding sitesA gene expression atlas of a bicoid-depleted Drosophila embryo reveals early canalization of cell fate.Shadow enhancers enable Hunchback bifunctionality in the Drosophila embryoQuantitative modeling of a gene's expression from its intergenic sequence.The cis-regulatory logic of Hedgehog gradient responses: key roles for gli binding affinity, competition, and cooperativity.Sequence-based model of gap gene regulatory network.Mid-embryo patterning and precision in Drosophila segmentation: Krüppel dual regulation of hunchback.Low-cost, low-input RNA-seq protocols perform nearly as well as high-input protocols.Evolutionary origins of transcription factor binding site clustersGlobal sensitivity analysis of a dynamic model for gene expression in Drosophila embryos.Dynamics of Transcription Factor Binding Site Evolution.Analysis of functional importance of binding sites in the Drosophila gap gene network model.A Systematic Ensemble Approach to Thermodynamic Modeling of Gene Expression from Sequence Data.Interactions between pluripotency factors specify cis-regulation in embryonic stem cellsA synergistic DNA logic predicts genome-wide chromatin accessibility.Noncommutative Biology: Sequential Regulation of Complex Networks.Sig2GRN: a software tool linking signaling pathway with gene regulatory network for dynamic simulationA model of spatially restricted transcription in opposing gradients of activators and repressorsReverse engineering systems models of regulation: discovery, prediction and mechanisms.Quantitative perturbation-based analysis of gene expression predicts enhancer activity in early Drosophila embryo.Systems biophysics of gene expression.
P2860
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P2860
Thermodynamics-based models of transcriptional regulation by enhancers: the roles of synergistic activation, cooperative binding and short-range repression.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Thermodynamics-based models of ...... ng and short-range repression.
@ast
Thermodynamics-based models of ...... ng and short-range repression.
@en
type
label
Thermodynamics-based models of ...... ng and short-range repression.
@ast
Thermodynamics-based models of ...... ng and short-range repression.
@en
prefLabel
Thermodynamics-based models of ...... ng and short-range repression.
@ast
Thermodynamics-based models of ...... ng and short-range repression.
@en
P2093
P2860
P1476
Thermodynamics-based models of ...... ng and short-range repression.
@en
P2093
Charles Blatti
Md Abul Hassan Samee
Saurabh Sinha
P2860
P356
10.1371/JOURNAL.PCBI.1000935
P577
2010-09-16T00:00:00Z