Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease. - Wikidata - awgldk - TriplyDB

Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease.

Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease.

http://www.wikidata.org/entity/Q33705025

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Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies The renal channelopathies Cell biology and pathology of podocytes Calcium regulates podocyte actin dynamics.TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex Inhibition of the TRPC5 ion channel protects the kidney filter Podocyte dysfunction in atypical haemolytic uraemic syndrome.Transient receptor potential (TRP) channels: a clinical perspective The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling.PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity.Single-channel analysis of TRPC channels in the podocytes of freshly isolated Glomeruli Expression of TRPC6 in renal cortex and hippocampus of mouse during postnatal development.Non-immunologic actions of calcineurin inhibitors in proteinuric kidney diseases.Genetic causes of proteinuria and nephrotic syndrome: impact on podocyte pathobiology.TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy Activation of RhoA in podocytes induces focal segmental glomerulosclerosis.Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.Gq signaling causes glomerular injury by activating TRPC6.Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species.Sustained activation of N-methyl-D-aspartate receptors in podoctyes leads to oxidative stress, mobilization of transient receptor potential canonical 6 channels, nuclear factor of activated T cells activation, and apoptotic cell death.Podocyte injury in diabetic nephropathy: implications of angiotensin II-dependent activation of TRPC channels Inhibition of TRPC6 by protein kinase C isoforms in cultured human podocytes Role of renal TRP channels in physiology and pathology Wnt/β-catenin signalling and podocyte dysfunction in proteinuric kidney disease.Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2)20-Hydroxyeicosatetraenoic Acid (20-HETE) Modulates Canonical Transient Receptor Potential-6 (TRPC6) Channels in Podocytes Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease.The proteoglycan syndecan 4 regulates transient receptor potential canonical 6 channels via RhoA/Rho-associated protein kinase signaling.Deletion of TRPC6 Attenuates NMDA Receptor-Mediated Ca2+ Entry and Ca2+-Induced Neurotoxicity Following Cerebral Ischemia and Oxygen-Glucose Deprivation.Tyrosine kinase signaling in kidney glomerular podocytes.Balancing calcium signals through TRPC5 and TRPC6 in podocytes.Educational paper: the podocytopathies.Animal models of nephrotic syndrome.How many Achilles' heels does a podocyte have? An update on podocyte biology.Podocyte directed therapy of nephrotic syndrome-can we bring the inside out?Pleiotropic signaling evoked by tumor necrosis factor in podocytes.ATP acting through P2Y receptors causes activation of podocyte TRPC6 channels: role of podocin and reactive oxygen species.Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol.Disease modeling in genetic kidney diseases: mice.

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P2860

Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease.

http://www.wikidata.org/entity/Q33705025

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Podocyte-specific overexpressi ...... t to cause glomerular disease.

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Podocyte-specific overexpressi ...... t to cause glomerular disease.

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type

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Podocyte-specific overexpressi ...... t to cause glomerular disease.

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Podocyte-specific overexpressi ...... t to cause glomerular disease.

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prefLabel

Podocyte-specific overexpressi ...... t to cause glomerular disease.

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Podocyte-specific overexpressi ...... t to cause glomerular disease.

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Podocyte-specific overexpressi ...... t to cause glomerular disease.

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Cesar P Canales

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Changli Wei

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J Daniel Carpio

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Jessica Molina

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Jing Li

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Jochen Reiser

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Juan I Young

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Paola Krall

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Phillip Ruiz

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P2860

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis

Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein

Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN

MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis

Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes

NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

The TRP channels, a remarkably functional family

Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. Ca(2+)-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor

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Paulina Carmona-Mora

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2010-09-20T00:00:00Z

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46579556

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