The beta1 subunit of the Na,K-ATPase pump interacts with megalencephalic leucoencephalopathy with subcortical cysts protein 1 (MLC1) in brain astrocytes: new insights into MLC pathogenesis
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Mutant GlialCAM causes megalencephalic leukoencephalopathy with subcortical cysts, benign familial macrocephaly, and macrocephaly with retardation and autismMegalencephalic leukoencephalopathy with subcortical cysts protein 1 functionally cooperates with the TRPV4 cation channel to activate the response of astrocytes to osmotic stress: dysregulation by pathological mutationsMegalencephalic leukoencephalopathy with subcortical cysts protein-1 modulates endosomal pH and protein trafficking in astrocytes: relevance to MLC disease pathogenesisAutism-epilepsy phenotype with macrocephaly suggests PTEN, but not GLIALCAM, genetic screening.GlialCAM, a protein defective in a leukodystrophy, serves as a ClC-2 Cl(-) channel auxiliary subunit.Chloride channelopathies of ClC-2.ASTROCYTES: EMERGING STARS IN LEUKODYSTROPHY PATHOGENESIS.MLC1 protein: a likely link between leukodystrophies and brain channelopathies.A transcriptome-based assessment of the astrocytic dystrophin-associated complex in the developing human brain.Megalencephalic leukoencephalopathy with subcortical cysts protein-1 regulates epidermal growth factor receptor signaling in astrocytes.Structural determinants of interaction, trafficking and function in the ClC-2/MLC1 subunit GlialCAM involved in leukodystrophy.Glial Na(+) -dependent ion transporters in pathophysiological conditions.Megalencephalic leukoencephalopathy with subcortical cysts protein 1 regulates glial surface localization of GLIALCAM from fish to humans.Genetically induced dysfunctions of Kir2.1 channels: implications for short QT3 syndrome and autism-epilepsy phenotype.Leukodystrophies: a proposed classification system based on pathological changes and pathogenetic mechanisms.Megalencephalic leukoencephalopathy with cysts: the Glialcam-null mouse modelInsights into MLC pathogenesis: GlialCAM is an MLC1 chaperone required for proper activation of volume-regulated anion currents.Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle.Astrocyte-mediated infantile-onset leukoencephalopathy mouse model.Depolarization causes the formation of a ternary complex between GlialCAM, MLC1 and ClC-2 in astrocytes: implications in megalencephalic leukoencephalopathy.Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier.Seizures and disturbed brain potassium dynamics in the leukodystrophy megalencephalic leukoencephalopathy with subcortical cysts.
P2860
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P2860
The beta1 subunit of the Na,K-ATPase pump interacts with megalencephalic leucoencephalopathy with subcortical cysts protein 1 (MLC1) in brain astrocytes: new insights into MLC pathogenesis
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The beta1 subunit of the Na,K- ...... insights into MLC pathogenesis
@ast
The beta1 subunit of the Na,K- ...... insights into MLC pathogenesis
@en
type
label
The beta1 subunit of the Na,K- ...... insights into MLC pathogenesis
@ast
The beta1 subunit of the Na,K- ...... insights into MLC pathogenesis
@en
prefLabel
The beta1 subunit of the Na,K- ...... insights into MLC pathogenesis
@ast
The beta1 subunit of the Na,K- ...... insights into MLC pathogenesis
@en
P2093
P2860
P50
P356
P1476
The beta1 subunit of the Na,K- ...... insights into MLC pathogenesis
@en
P2093
Angela Lanciotti
Gianfranco Macchia
Matteo Gaetani
Tamara C Petrucci
P2860
P304
P356
10.1093/HMG/DDQ435
P577
2010-10-06T00:00:00Z