Task2 potassium channels set central respiratory CO2 and O2 sensitivity. - Wikidata - awgldk - TriplyDB

Task2 potassium channels set central respiratory CO2 and O2 sensitivity.

Task2 potassium channels set central respiratory CO2 and O2 sensitivity.

http://www.wikidata.org/entity/Q33719818

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Gating of a pH-sensitive K(2P) potassium channel by an electrostatic effect of basic sensor residues on the selectivity filter Separate gating mechanisms mediate the regulation of K2P potassium channel TASK-2 by intra- and extracellular pH Proton detection and breathing regulation by the retrotrapezoid nucleus.Neural Control of Breathing and CO2 Homeostasis.The retrotrapezoid nucleus stimulates breathing by releasing glutamate in adult conscious mice PHYSIOLOGY. Regulation of breathing by CO₂ requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons.State-dependent control of breathing by the retrotrapezoid nucleus.Hypoxia silences retrotrapezoid nucleus respiratory chemoreceptors via alkalosis.Regulation of breathing and autonomic outflows by chemoreceptors.The role of pH-sensitive TASK channels in central respiratory chemoreception.KCNK5 channels mostly expressed in cochlear outer sulcus cells are indispensable for hearing External pH modulates EAG superfamily K+ channels through EAG-specific acidic residues in the voltage sensor TASK-2 channels contribute to pH sensitivity of retrotrapezoid nucleus chemoreceptor neurons.Central respiratory chemoreception.Central chemoreceptors: locations and functions.Anesthetic activation of central respiratory chemoreceptor neurons involves inhibition of a THIK-1-like background K(+) current.An interdependent model of central/peripheral chemoreception: evidence and implications for ventilatory control.Genetic inactivation of Kcnj16 identifies Kir5.1 as an important determinant of neuronal PCO2/pH sensitivity.Molecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels.Remote control of respiratory neural network by spinal locomotor generators The two-pore domain potassium channel KCNK5: induction by estrogen receptor alpha and role in proliferation of breast cancer cells.Adenosine A₂a receptors and O₂ sensing in development Julius H. Comroe, Jr., distinguished lecture: central chemoreception: then ... and now.Specific neural substrate linking respiration to locomotion.A Phox2b BAC Transgenic Rat Line Useful for Understanding Respiratory Rhythm Generator Neural Circuitry.Neurobiology of panic and pH chemosensation in the brain.Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy.Murine K2P5.1 Deficiency Has No Impact on Autoimmune Neuroinflammation due to Compensatory K2P3.1- and KV1.3-Dependent Mechanisms Identifying Candidate Genes that Underlie Cellular pH Sensitivity in Serotonin Neurons Using Transcriptomics: A Potential Role for Kir5.1 Channels.The cellular building blocks of breathing TASK-1 (KCNK3) and TASK-3 (KCNK9) tandem pore potassium channel antagonists stimulate breathing in isoflurane-anesthetized rats.Peripheral chemoreceptors: function and plasticity of the carotid body.THIK-1 (K2P13.1) is a small-conductance background K(+) channel in rat trigeminal ganglion neurons.Ionic mechanisms of central CO(2) chemosensitivity.Molecular physiology of pH-sensitive background K(2P) channels.The two-pore domain potassium channel KCNK5 deteriorates outcome in ischemic neurodegeneration.TASK-2 K₂p K⁺ channel: thoughts about gating and its fitness to physiological function.The CNS under pathophysiologic attack--examining the role of K₂p channels.The family of K2P channels: salient structural and functional properties.Much more than a leak: structure and function of K₂p-channels.

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P2860

Task2 potassium channels set central respiratory CO2 and O2 sensitivity.

http://www.wikidata.org/entity/Q33719818

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

@zh-tw

2010年论文

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name

Task2 potassium channels set central respiratory CO2 and O2 sensitivity.

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Task2 potassium channels set central respiratory CO2 and O2 sensitivity.

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type

label

Task2 potassium channels set central respiratory CO2 and O2 sensitivity.

@ast

Task2 potassium channels set central respiratory CO2 and O2 sensitivity.

@en

prefLabel

Task2 potassium channels set central respiratory CO2 and O2 sensitivity.

@ast

Task2 potassium channels set central respiratory CO2 and O2 sensitivity.

@en

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PNAS.0910059107

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Task2 potassium channels set central respiratory CO2 and O2 sensitivity

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P2093

Christina Sterner

http://www.w3.org/2001/XMLSchema#string

Christo Goridis

http://www.w3.org/2001/XMLSchema#string

Chérif Benfriha

http://www.w3.org/2001/XMLSchema#string

Dirk Heitzmann

http://www.w3.org/2001/XMLSchema#string

Hannah Ehnes

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Ines Tegtmeier

http://www.w3.org/2001/XMLSchema#string

Jacques Barhanin

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Joerg Thomas

http://www.w3.org/2001/XMLSchema#string

Julie Peyronnet-Roux

http://www.w3.org/2001/XMLSchema#string

Markus Reichold

http://www.w3.org/2001/XMLSchema#string

P2860

Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney

Polyalanine expansion and frameshift mutations of the paired-like homeobox gene PHOX2B in congenital central hypoventilation syndrome

An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells

Breathing: rhythmicity, plasticity, chemosensitivity

The TASK-1 two-pore domain K+ channel is a molecular substrate for neuronal effects of inhalation anesthetics.

Cns distribution of members of the two-pore-domain (KCNK) potassium channel family.

Glutamatergic neuronal projections from the marginal layer of the rostral ventral medulla to the respiratory centers in rats.

Respiratory control by ventral surface chemoreceptor neurons in rats.

A human mutation in Phox2b causes lack of CO2 chemosensitivity, fatal central apnea, and specific loss of parafacial neurons.

Afferent and efferent connections of the rat retrotrapezoid nucleus.

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2325-2330

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10.1073/PNAS.0910059107

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5

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107

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Christian Gestreau

Jean-François Brunet

Véronique Dubreuil

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2010-01-19T00:00:00Z

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41408727

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20133877

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2836670

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