P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.
about
Cytochromes P450: a success storyAltered gene expression in human cells treated with the insecticide diazinon: correlation with decreased DNA excision repair capacityReciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CARThe xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CARThe chemical defensome: environmental sensing and response genes in the Strongylocentrotus purpuratus genomeEffects of perinatal PBDE exposure on hepatic phase I, phase II, phase III, and deiodinase 1 gene expression involved in thyroid hormone metabolism in male rat pupsEvidence of an interaction between nifedipine and nafcillin in humansComplex effects of rexinoids on ligand dependent activation or inhibition of the xenobiotic receptor, CARUnderstanding the human health effects of chemical mixtures.Roles of rifampicin in drug-drug interactions: underlying molecular mechanisms involving the nuclear pregnane X receptor.Drug-Induced Liver Toxicity and Prevention by Herbal Antioxidants: An OverviewControversies in contraception for women with epilepsyModulation of xenobiotic receptors by steroidsDual-color fluorescence imaging to monitor CYP3A4 and CYP3A7 expression in human hepatic carcinoma HepG2 and HepaRG cellsToxicity testing in the 21st century: a vision and a strategyRegulation of drug-metabolizing enzymes by local and systemic liver injuriesKey Targets for Multi-Target Ligands Designed to Combat NeurodegenerationHuman apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome proliferator-activated receptor alphaDehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gammaXenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligandsTranscriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery diseaseInduction of cytochrome P450 enzymes in rat liver by two conazoles, myclobutanil and triadimefonThe CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligandsFunctional interactions between an atypical NF-kappaB site from the rat CYP2B1 promoter and the transcriptional repressor RBP-Jkappa/CBF1.Hepatotoxicity of targeted therapy for cancer.Role of nuclear receptor SHP in metabolism and cancer.The use of quantitative histological and molecular data for risk assessment and biologically based model development.Drugs mediate the transcriptional activation of the 5-aminolevulinic acid synthase (ALAS1) gene via the chicken xenobiotic-sensing nuclear receptor (CXR).Pharmacogenomic characterization of gemcitabine response--a framework for data integration to enable personalized medicine.Integration of transcriptome and whole genomic resequencing data to identify key genes affecting swine fat depositionCytochrome P450 CYP2 genes in the common cormorant: Evolutionary relationships with 130 diapsid CYP2 clan sequences and chemical effects on their expressionProbing enhanced cytochrome P450 2B1/2 activity in rat hepatocyte spheroids through confocal laser scanning microscopy.Availability of specific reductases controls the temporal activity of the cytochrome P450 complement of Streptomyces coelicolor A3(2).The cytochrome P450 (CYP) gene superfamily in Daphnia pulexGenome-wide identification and characterization of cytochrome P450 monooxygenase genes in the ciliate Tetrahymena thermophila.Functional interactions between cytochromes P450 1A2 and 2B4 require both enzymes to reside in the same phospholipid vesicle: evidence for physical complex formation.On the general mechanism of selective induction of cytochrome P450 enzymes by chemicals: some theoretical considerations.Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish
P2860
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P2860
P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
P450 gene induction by structu ...... receptors CAR, PXR, and PPAR.
@ast
P450 gene induction by structu ...... receptors CAR, PXR, and PPAR.
@en
type
label
P450 gene induction by structu ...... receptors CAR, PXR, and PPAR.
@ast
P450 gene induction by structu ...... receptors CAR, PXR, and PPAR.
@en
prefLabel
P450 gene induction by structu ...... receptors CAR, PXR, and PPAR.
@ast
P450 gene induction by structu ...... receptors CAR, PXR, and PPAR.
@en
P356
P1476
P450 gene induction by structu ...... receptors CAR, PXR, and PPAR.
@en
P356
10.1006/ABBI.1999.1351
P407
P577
1999-09-01T00:00:00Z