Loss of function of ATXN1 increases amyloid beta-protein levels by potentiating beta-secretase processing of beta-amyloid precursor protein.
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Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathwayThe genetics of Alzheimer diseaseAn out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting proteinConcerted perturbation observed in a hub network in Alzheimer's diseaseThe epigenetic dimension of Alzheimer's disease: causal, consequence, or curiosity?The vasculome of the mouse brain.Amyloid-β production via cleavage of amyloid-β protein precursor is modulated by cell density.Cathepsin L Mediates the Degradation of Novel APP C-Terminal Fragments.Massachusetts Alzheimer's Disease Research Center: progress and challenges.Analysis of copy number variation in Alzheimer's disease: the NIALOAD/ NCRAD Family StudyDesign and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer's diseaseNeuron membrane trafficking and protein kinases involved in autism and ADHD.A preliminary study on methylphenidate-regulated gene expression in lymphoblastoid cells of ADHD patients.Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).A generally applicable translational strategy identifies S100A4 as a candidate gene in allergy.6p22.3 deletion: report of a patient with autism, severe intellectual disability and electroencephalographic anomalies.Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein.Soluble Gamma-secretase Modulators Attenuate Alzheimer's β-amyloid Pathology and Induce Conformational Changes in Presenilin 1.RNAi screen identifies essential regulators of human brain metastasis-initiating cells.Cromolyn Reduces Levels of the Alzheimer's Disease-Associated Amyloid β-Protein by Promoting Microglial Phagocytosis.A novel function of Ataxin-1 in the modulation of PP2A activity is dysregulated in the spinocerebellar ataxia type 1.Mechanisms that synergistically regulate η-secretase processing of APP and Aη-α protein levels: relevance to pathogenesis and treatment of Alzheimer's disease.Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
P2860
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P2860
Loss of function of ATXN1 increases amyloid beta-protein levels by potentiating beta-secretase processing of beta-amyloid precursor protein.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Loss of function of ATXN1 incr ...... eta-amyloid precursor protein.
@ast
Loss of function of ATXN1 incr ...... eta-amyloid precursor protein.
@en
type
label
Loss of function of ATXN1 incr ...... eta-amyloid precursor protein.
@ast
Loss of function of ATXN1 incr ...... eta-amyloid precursor protein.
@en
prefLabel
Loss of function of ATXN1 incr ...... eta-amyloid precursor protein.
@ast
Loss of function of ATXN1 incr ...... eta-amyloid precursor protein.
@en
P2093
P2860
P356
P1476
Loss of function of ATXN1 incr ...... beta-amyloid precursor protein
@en
P2093
Andrew Browne
Jason R Divito
Jesse A Stevenson
P2860
P304
P356
10.1074/JBC.M109.079079
P407
P577
2010-01-22T00:00:00Z