Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein. - Wikidata - awgldk - TriplyDB

Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein.

Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein.

http://www.wikidata.org/entity/Q42214633

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Curcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st century The Role of Oxidative Damage in the Pathogenesis and Progression of Alzheimer's Disease and Vascular Dementia A combination cocktail improves spatial attention in a canine model of human aging and Alzheimer's disease.Curcumin prevents formation of polyglutamine aggregates by inhibiting Vps36, a component of the ESCRT-II complex.Challenging oneself intermittently to improve health.Protective effects of curcumin in APPswe transfected SH-SY5Y cells Histone acetyltransferase p300 mediates histone acetylation of PS1 and BACE1 in a cellular model of Alzheimer's disease.Dementia and Alzheimer's disease: a new direction.The 2010 Jay L. Foster Memorial Lecture.Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation.Amyloid-β production via cleavage of amyloid-β protein precursor is modulated by cell density.Controlled systemic delivery by polymeric implants enhances tissue and plasma curcumin levels compared with oral administration.Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease.Turmeric and curcumin suppress presenilin 1 protein expression in Jurkat cells Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people.Curcumin and neurodegenerative diseases.Curcumin: a natural substance with potential efficacy in Alzheimer's disease.Amyloidosis in Alzheimer's Disease: The Toxicity of Amyloid Beta (A β ), Mechanisms of Its Accumulation and Implications of Medicinal Plants for Therapy The effect of cyclodextrin-solubilized curcuminoids on amyloid plaques in Alzheimer transgenic mice: brain uptake and metabolism after intravenous and subcutaneous injection.Lessons from two prevalent amyloidoses-what amylin and Aβ have in common Medicinal chemistry of the epigenetic diet and caloric restriction.Challenges associated with curcumin therapy in Alzheimer disease.Curcumin and neurodegenerative diseases: a perspective.Therapeutic potential of turmeric in Alzheimer's disease: curcumin or curcuminoids?Diets involved in PPAR and PI3K/AKT/PTEN pathway may contribute to neuroprotection in a traumatic brain injury.Natural polyphenols binding to amyloid: a broad class of compounds to treat different human amyloid diseases.Clinical development of curcumin in neurodegenerative disease.Lifestyle Modulators of Neuroplasticity: How Physical Activity, Mental Engagement, and Diet Promote Cognitive Health during Aging.Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease.α-Mangostin decreases β-amyloid peptides production via modulation of amyloidogenic pathway.Dicyanovinyl-substituted J147 analogue inhibits oligomerization and fibrillation of β-amyloid peptides and protects neuronal cells from β-amyloid-induced cytotoxicity.Inhibitory effect of chloroquine derivatives on presenilin 1 and ubiquilin 1 expression in Alzheimer's disease.Protection of curcumin against amyloid-β-induced cell damage and death involves the prevention from NMDA receptor-mediated intracellular Ca2+ elevation.Curcumin protects neuronal-like cells against acrolein by restoring Akt and redox signaling pathways.Flavanones: Citrus phytochemical with health-promoting properties.Can healthy lifestyle modify risk factors for dementia? Findings from a pilot community-based survey in Chennai (India) and Newcastle (UK).Nanoplasmonic fiber tip probe detects significant reduction of intracellular Alzheimer's disease-related oligomers by curcumin.Natural Modulators of Amyloid-Beta Precursor Protein Processing.Curcumin and Alzheimer disease: this marriage is not to be performed.Soluble Gamma-secretase Modulators Attenuate Alzheimer's β-amyloid Pathology and Induce Conformational Changes in Presenilin 1.Mechanisms and effects of curcumin on spatial learning and memory improvement in APPswe/PS1dE9 mice.

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Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein.

http://www.wikidata.org/entity/Q42214633

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Curcumin decreases amyloid-bet ...... myloid-beta precursor protein.

@en

Curcumin decreases amyloid-bet ...... myloid-beta precursor protein.

@nl

type

label

Curcumin decreases amyloid-bet ...... myloid-beta precursor protein.

@en

Curcumin decreases amyloid-bet ...... myloid-beta precursor protein.

@nl

prefLabel

Curcumin decreases amyloid-bet ...... myloid-beta precursor protein.

@en

Curcumin decreases amyloid-bet ...... myloid-beta precursor protein.

@nl

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JBC.M110.133520

P1433

Journal of Biological Chemistry

P1476

Curcumin decreases amyloid-bet ...... amyloid-beta precursor protein

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P2093

Andrew Browne

http://www.w3.org/2001/XMLSchema#string

Can Zhang

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P2860

Localization and functional analyses of the MLC1 protein involved in megalencephalic leukoencephalopathy with subcortical cysts

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Alzheimer's disease: genes, proteins, and therapy

gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins

Alzheimer's disease is a synaptic failure

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

Development and validation of a high-density fluorescence polarization-based assay for the trypanosoma RNA triphosphatase TbCet1.

Loss of function of ATXN1 increases amyloid beta-protein levels by potentiating beta-secretase processing of beta-amyloid precursor protein.

The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease.

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28472-28480

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10.1074/JBC.M110.133520

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37

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285

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Rudolph E. Tanzi

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2010-07-09T00:00:00Z

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20622013

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2937872

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