Oxysterols from free radical chain oxidation of 7-dehydrocholesterol: product and mechanistic studies.
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An oxysterol biomarker for 7-dehydrocholesterol oxidation in cell/mouse models for Smith-Lemli-Opitz syndromeLipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndrome7-Dehydrocholesterol-derived oxysterols and retinal degeneration in a rat model of Smith-Lemli-Opitz syndromeNanostructure-initiator mass spectrometry (NIMS) imaging of brain cholesterol metabolites in Smith-Lemli-Opitz syndromeSterols and oxysterols in plasma from Smith-Lemli-Opitz syndrome patientsThe Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human FibroblastsIsolated Conglutin γ from Lupin, but not Phytate, Lowers Serum Cholesterol Without Influencing Vascular Lesion Development in the ApoE-deficient Mouse Model.Biological activities of 7-dehydrocholesterol-derived oxysterols: implications for Smith-Lemli-Opitz syndromeThe ins and outs of cholesterol in the vertebrate retina.Antioxidant supplementation ameliorates molecular deficits in Smith-Lemli-Opitz syndromeMalformation syndromes caused by disorders of cholesterol synthesis.Elevated Autophagy and Mitochondrial Dysfunction in the Smith-Lemli-Opitz Syndrome.Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome.Novel oxysterols observed in tissues and fluids of AY9944-treated rats: a model for Smith-Lemli-Opitz syndrome.Profiling and Imaging Ion Mobility-Mass Spectrometry Analysis of Cholesterol and 7-Dehydrocholesterol in Cells Via Sputtered Silver MALDIFree radical oxidation of cholesterol and its precursors: Implications in cholesterol biosynthesis disorders.Inhibitors of 7-Dehydrocholesterol Reductase: Screening of a Collection of Pharmacologically Active Compounds in Neuro2a Cells.Tunneling in tocopherol-mediated peroxidation of 7-dehydrocholesterol.No evidence for mevalonate shunting in moderately affected children with Smith-Lemli-Opitz syndromeOxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1.Assays of plasma dehydrocholesteryl esters and oxysterols from Smith-Lemli-Opitz syndrome patientsMetabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells.DHCEO accumulation is a critical mediator of pathophysiology in a Smith-Lemli-Opitz syndrome modelA perspective on free radical autoxidation: the physical organic chemistry of polyunsaturated fatty acid and sterol peroxidation.Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis.A highly sensitive method for analysis of 7-dehydrocholesterol for the study of Smith-Lemli-Opitz syndromeProbes for protein adduction in cholesterol biosynthesis disorders: Alkynyl lanosterol as a viable sterol precursor.Reactivities and products of free radical oxidation of cholestadienols.Analysis by liquid chromatography-mass spectrometry of sterols and oxysterols in brain of the newborn Dhcr7(Δ3-5/T93M) mouse: a model of Smith-Lemli-Opitz syndrome.Conversion of 7-dehydrocholesterol to 7-ketocholesterol is catalyzed by human cytochrome P450 7A1 and occurs by direct oxidation without an epoxide intermediate.Oxidative stress, serotonergic changes and decreased ultrasonic vocalizations in a mouse model of Smith-Lemli-Opitz syndrome.Differential cytotoxic effects of 7-dehydrocholesterol-derived oxysterols on cultured retina-derived cells: Dependence on sterol structure, cell type, and density.Smith-Lemli-Opitz syndrome.Antioxidants: The Missing Key to Improved Therapeutic Intervention in Smith-Lemli-Opitz Syndrome?UV-irradiated 7-dehydrocholesterol coating on polystyrene surfaces is converted to active vitamin D by osteoblastic MC3T3-E1 cells.Vulnerability of DHCR7+/- mutation carriers to aripiprazole and trazodone exposure.Prevention of Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome.Propagation rate constants for the peroxidation of sterols on the biosynthetic pathway to cholesterol.Biochemical properties of cholesterol aldehyde secosterol and its derivatives.Oxysterols and Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome: Implications for an Improved Therapeutic Intervention
P2860
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P2860
Oxysterols from free radical chain oxidation of 7-dehydrocholesterol: product and mechanistic studies.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Oxysterols from free radical c ...... oduct and mechanistic studies.
@ast
Oxysterols from free radical c ...... oduct and mechanistic studies.
@en
type
label
Oxysterols from free radical c ...... oduct and mechanistic studies.
@ast
Oxysterols from free radical c ...... oduct and mechanistic studies.
@en
prefLabel
Oxysterols from free radical c ...... oduct and mechanistic studies.
@ast
Oxysterols from free radical c ...... oduct and mechanistic studies.
@en
P2860
P356
P1476
Oxysterols from free radical c ...... roduct and mechanistic studies
@en
P2093
Ned A Porter
P2860
P304
P356
10.1021/JA9080265
P407
P577
2010-02-01T00:00:00Z