Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertions.
about
HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBECIntracellular immunity to HIV-1: newly defined retroviral battles inside infected cells.Viral quasispecies evolutionHIV-1 reverse transcriptionResponse of foot-and-mouth disease virus to increased mutagenesis: influence of viral load and fitness in loss of infectivity5-Azacytidine and RNA secondary structure increase the retrovirus mutation rateCross- and Co-Packaging of Retroviral RNAs and Their ConsequencesThe antiretrovirus drug 3'-azido-3'-deoxythymidine increases the retrovirus mutation ratePremature strand transfer by the HIV-1 reverse transcriptase during strong-stop DNA synthesisFootprint of APOBEC3 on the genome of human retroelementsHIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapyLower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptaseEvidence for the acquisition of multi-drug resistance in an HIV-1 clinical isolate via human sequence transductionSelection and characterization of replication-competent revertants of a Rous sarcoma virus src gene oversplicing mutant.3'-Azido-3'-deoxythymidine (AZT) and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of human immunodeficiency virus type 1.Unselected mutations in the human immunodeficiency virus type 1 genome are mostly nonsynonymous and often deleteriousMolecular evolution of human immunodeficiency virus type 1 upon transmission between human leukocyte antigen disparate donor-recipient pairs.Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrantsThe 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity.Host-specific modulation of the selective constraints driving human immunodeficiency virus type 1 env gene evolution.A functional screen for regulatory elements that improve retroviral vector gene expressionMechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3'LTR.Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts, and hypermutationsAn array of novel murine spleen focus-forming viruses that activate the erythropoietin receptor.Relative rates of retroviral reverse transcriptase template switching during RNA- and DNA-dependent DNA synthesis.Deoxyribonucleoside triphosphate pool imbalances in vivo are associated with an increased retroviral mutation rateDevelopment of an in vivo assay to identify structural determinants in murine leukemia virus reverse transcriptase important for fidelityStructural determinants of murine leukemia virus reverse transcriptase that affect the frequency of template switchingIn vivo analysis of human T-cell leukemia virus type 1 reverse transcription accuracy.Effect of distance between homologous sequences and 3' homology on the frequency of retroviral reverse transcriptase template switching.Development of murine leukemia virus-based self-activating vectors that efficiently delete the selectable drug resistance gene during reverse transcription.Effects of homology length in the repeat region on minus-strand DNA transfer and retroviral replication.Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors.Moloney murine sarcoma virus MuSVts110 DNA: cloning, nucleotide sequence, and gene expressionDynamic copy choice: steady state between murine leukemia virus polymerase and polymerase-dependent RNase H activity determines frequency of in vivo template switching.Decreased virus population diversity in p53-null mice infected with weakly oncogenic Abelson virus.Homologous recombination promoted by reverse transcriptase during copying of two distinct RNA templates.Y586F mutation in murine leukemia virus reverse transcriptase decreases fidelity of DNA synthesis in regions associated with adenine-thymine tracts.Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication.Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity.
P2860
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P2860
Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertions.
description
1990 nî lūn-bûn
@nan
1990 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Broad spectrum of in vivo forw ...... and deletions with insertions.
@ast
Broad spectrum of in vivo forw ...... and deletions with insertions.
@en
type
label
Broad spectrum of in vivo forw ...... and deletions with insertions.
@ast
Broad spectrum of in vivo forw ...... and deletions with insertions.
@en
prefLabel
Broad spectrum of in vivo forw ...... and deletions with insertions.
@ast
Broad spectrum of in vivo forw ...... and deletions with insertions.
@en
P2860
P356
P1476
Broad spectrum of in vivo forw ...... and deletions with insertions.
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.16.6024
P407
P577
1990-08-01T00:00:00Z