Stem cell-specific activation of an ancestral myc protooncogene with conserved basic functions in the early metazoan Hydra
about
The Quest for Targets Executing MYC-Dependent Cell TransformationMulti-functionality and plasticity characterize epithelial cells in HydraThe "virgin birth", polyploidy, and the origin of cancerHymyc1 downregulation promotes stem cell proliferation in Hydra vulgaris2′-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click LabelingCancer tumors as Metazoa 1.0: tapping genes of ancient ancestorsElectrostatic stabilization of a native protein structure in the gas phaseSomatic polyploidy is associated with the upregulation of c-MYC interacting genes and EMT-like signatureHydra myc2, a unique pre-bilaterian member of the myc gene family, is activated in cell proliferation and gametogenesis.Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation.A genomic view of 500 million years of cnidarian evolutionOrigins of Myc proteins--using intrinsic protein disorder to trace distant relatives.Premetazoan ancestry of the Myc-Max networkHydra as a tractable, long-lived model system for senescence.Loss of neurogenesis in Hydra leads to compensatory regulation of neurogenic and neurotransmission genes in epithelial cells.Neuroblastoma and MYCNConservation and divergence of bHLH genes in the calcisponge Sycon ciliatum.An overview of MYC and its interactome.Stem cells: a view from the roots.Stem cell dynamics in Cnidaria: are there unifying principles?Methodological approaches for nanotoxicology using cnidarian models.Stem cells and aging from a quasi-immortal point of view.Postembryonic organogenesis of the digestive tube: why does it occur in worms and sea cucumbers but fail in humans?Biochemical and Structural Characterization of the Interaction between the Siderocalin NGAL/LCN2 (Neutrophil Gelatinase-associated Lipocalin/Lipocalin 2) and the N-terminal Domain of Its Endocytic Receptor SLC22A17.Expanding the Scope of 2'-SCF3 Modified RNA.Chemical synthesis of site-specifically 2'-azido-modified RNA and potential applications for bioconjugation and RNA interference.Efficient access to 3'-terminal azide-modified RNA for inverse click-labeling patterns.Transcriptional control of DNA replication licensing by Myc.Unfolding and Folding of the Three-Helix Bundle Protein KIX in the Absence of Solvent.Analyzing Myc in cell transformation and evolution.Electron detachment dissociation for top-down mass spectrometry of acidic proteins.Molecular signatures of the three stem cell lineages in hydra and the emergence of stem cell function at the base of multicellularity.N-Lauroylation during the Expression of Recombinant N-Myristoylated Proteins: Implications and Solutions.Nanotoxicology using the sea anemone Nematostella vectensis: from developmental toxicity to genotoxicology.MYC and RAF: Key Effectors in Cellular Signaling and Major Drivers in Human Cancer.Characterization of the bHLH family of transcriptional regulators in the acoel S. roscoffensis and their putative role in neurogenesis.Annals of morphology. Atavisms: phylogenetic Lazarus?Mammalian MYC Proteins and Cancer
P2860
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P2860
Stem cell-specific activation of an ancestral myc protooncogene with conserved basic functions in the early metazoan Hydra
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Stem cell-specific activation ...... ns in the early metazoan Hydra
@ast
Stem cell-specific activation ...... ns in the early metazoan Hydra
@en
type
label
Stem cell-specific activation ...... ns in the early metazoan Hydra
@ast
Stem cell-specific activation ...... ns in the early metazoan Hydra
@en
prefLabel
Stem cell-specific activation ...... ns in the early metazoan Hydra
@ast
Stem cell-specific activation ...... ns in the early metazoan Hydra
@en
P2093
P2860
P356
P1476
Stem cell-specific activation ...... ns in the early metazoan Hydra
@en
P2093
Anna-Maria Mitterstiller
Bert Hobmayer
Kathrin Breuker
Klaus Bister
Markus Hartl
Taras Valovka
P2860
P304
P356
10.1073/PNAS.0911060107
P407
P577
2010-02-08T00:00:00Z