Premetazoan ancestry of the Myc-Max network - Wikidata - awgldk - TriplyDB

Premetazoan ancestry of the Myc-Max network

Premetazoan ancestry of the Myc-Max network

http://www.wikidata.org/entity/Q35468637

about

The Quest for Targets Executing MYC-Dependent Cell Transformation Functional interactions among members of the MAX and MLX transcriptional network during oncogenesis Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC N-Myc and L-Myc are essential for hair cell formation but not maintenance Bacterial influences on animal origins The cell survival pathways of the primordial RNA-DNA complex remain conserved in the extant genomes and may function as proto-oncogenes Correct timing of proliferation and differentiation is necessary for normal inner ear development and auditory hair cell viability.Understanding the evolution and development of neurosensory transcription factors of the ear to enhance therapeutic translation.Hydra myc2, a unique pre-bilaterian member of the myc gene family, is activated in cell proliferation and gametogenesis.Molecular evolution of the Yap/Yorkie proto-oncogene and elucidation of its core transcriptional program.The Capsaspora genome reveals a complex unicellular prehistory of animals Genome and transcriptome of the regeneration-competent flatworm, Macrostomum lignano.Origins of Myc proteins--using intrinsic protein disorder to trace distant relatives.Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages.Stabilization of HIF-1α and HIF-2α, up-regulation of MYCC and accumulation of stabilized p53 constitute hallmarks of CNS-PNET animal model Conservation and divergence of bHLH genes in the calcisponge Sycon ciliatum.An overview of MYC and its interactome.Transcriptional control of DNA replication licensing by Myc.The origin of Metazoa: a unicellular perspective.Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions The Origin of Animal Multicellularity and Cell Differentiation.The maternal-zygotic transition and zygotic activation of the Mnemiopsis leidyi genome occurs within the first three cleavage cycles.Sponges: A Reservoir of Genes Implicated in Human Cancer.MYC leads the way.MYC and RAF: Key Effectors in Cellular Signaling and Major Drivers in Human Cancer.Differentiation therapy and the mechanisms that terminate cancer cell proliferation without harming normal cells Mammalian MYC Proteins and Cancer

P2860

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P2860

Premetazoan ancestry of the Myc-Max network

http://www.wikidata.org/entity/Q35468637

description

2011 nî lūn-bûn

@nan

2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Premetazoan ancestry of the Myc-Max network

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Premetazoan ancestry of the Myc-Max network

@en

type

label

Premetazoan ancestry of the Myc-Max network

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Premetazoan ancestry of the Myc-Max network

@en

prefLabel

Premetazoan ancestry of the Myc-Max network

@ast

Premetazoan ancestry of the Myc-Max network

@en

P1433

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P1433

Molecular Biology and Evolution

P1476

Premetazoan ancestry of the Myc-Max network

@en

P2093

Daniel Diolaiti

http://www.w3.org/2001/XMLSchema#string

Maralice Conacci-Sorrell

http://www.w3.org/2001/XMLSchema#string

Nicole King

http://www.w3.org/2001/XMLSchema#string

Robert N Eisenman

http://www.w3.org/2001/XMLSchema#string

Susan L Young

http://www.w3.org/2001/XMLSchema#string

P2860

Evolution of the holozoan ribosome biogenesis regulon

The Amphimedon queenslandica genome and the evolution of animal complexity

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins

The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc

The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro

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2961-2971

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scholarly article

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10.1093/MOLBEV/MSR132

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10

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28

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Iñaki Ruiz-trillo

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2011-05-13T00:00:00Z

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51126446

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21571926

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P932

3203627

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