Selective targeting of radiation-resistant tumor-initiating cells. - Wikidata - awgldk - TriplyDB

Selective targeting of radiation-resistant tumor-initiating cells.

Selective targeting of radiation-resistant tumor-initiating cells.

http://www.wikidata.org/entity/Q33734733

about

Mammary Development and Breast Cancer: A Wnt Perspective Cancer stem cells and signaling pathways in radioresistance The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes Epithelial-mesenchymal plasticity of breast cancer stem cells: implications for metastasis and therapeutic resistance Identifying and targeting tumor-initiating cells in the treatment of breast cancer Cancer stem cells and radioresistance Epigenetics meets radiation biology as a new approach in cancer treatment Activation of the canonical Wnt/β-catenin pathway in ATF3-induced mammary tumors A phenotypic mouse model of basaloid breast tumors The antihelmintic drug pyrvinium pamoate targets aggressive breast cancer Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer.Histone deacetylase inhibitors stimulate dedifferentiation of human breast cancer cells through WNT/β-catenin signaling.Targeting hypoxic microenvironment of pancreatic xenografts with the hypoxia-activated prodrug TH-302.Cancer stem cell markers are enriched in normal tissue adjacent to triple negative breast cancer and inversely correlated with DNA repair deficiency.Lung cancer stem cell: new insights on experimental models and preclinical data.Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential Differentiation generates paracrine cell pairs that maintain basaloid mouse mammary tumors: proof of concept.Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy Nuclear localizaiton of β-catenin is associated with poor survival and chemo-/radioresistance in human cervical squamous cell cancer.Ionizing radiation induces stemness in cancer cells Chloroquine or chloroquine-PI3K/Akt pathway inhibitor combinations strongly promote γ-irradiation-induced cell death in primary stem-like glioma cells Single unpurified breast tumor-initiating cells from multiple mouse models efficiently elicit tumors in immune-competent hosts.Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway.Inhibition of transient receptor potential channel 5 reverses 5-Fluorouracil resistance in human colorectal cancer cells.DNA repair: the culprit for tumor-initiating cell survival?Associating GWAS Information with the Notch Signaling Pathway Using Transcription Profiling.Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity.Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression.Mammary cells with active Wnt signaling resist ErbB2-induced tumorigenesis Radiation promotes malignant phenotypes through SRC in breast cancer cells.A 3D multiscale model of cancer stem cell in tumor development.Metastatic breast cancer cells in the bone marrow microenvironment: novel insights into oncoprotection.Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival.Intratumoral heterogeneity in a Trp53-null mouse model of human breast cancer.Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy.Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells.Targeting DDX3 with a small molecule inhibitor for lung cancer therapy.On murine mammary epithelial stem cells: discovery, function, and current status Immunobiology and signaling pathways of cancer stem cells: implication for cancer therapy.Sensitization of pancreatic cancer stem cells to gemcitabine by Chk1 inhibition.

P2860

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P2860

Selective targeting of radiation-resistant tumor-initiating cells.

http://www.wikidata.org/entity/Q33734733

description

2010 nî lūn-bûn

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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

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2010年论文

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name

Selective targeting of radiation-resistant tumor-initiating cells.

@ast

Selective targeting of radiation-resistant tumor-initiating cells.

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type

label

Selective targeting of radiation-resistant tumor-initiating cells.

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Selective targeting of radiation-resistant tumor-initiating cells.

@en

prefLabel

Selective targeting of radiation-resistant tumor-initiating cells.

@ast

Selective targeting of radiation-resistant tumor-initiating cells.

@en

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Proceedings of the National Academy of Sciences of the United States of America

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Selective targeting of radiation-resistant tumor-initiating cells.

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Jeffrey M Rosen

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Mei Zhang

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Rachel L Atkinson

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P2860

Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours

Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy

PTEN-deficient intestinal stem cells initiate intestinal polyposis.

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR

Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling

A role for Wnt signalling in self-renewal of haematopoietic stem cells

Generation of a functional mammary gland from a single stem cell

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