The rational design of potential chemotherapeutic agents: synthesis of bryostatin analogues.
about
Total synthesis of bryostatin 7 via C-C bond-forming hydrogenationSearch and discovery strategies for biotechnology: the paradigm shift.Marine-derived anticancer agents in clinical trials.Identifying bryostatins and potential precursors from the bryozoan Bugula neritina.Impact of environmental conditions on the marine natural product bryostatin 1.Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivityMarine natural products: bryostatins in preclinical and clinical studies.Synthetic studies on the bryostatins: synthetic routes to analogues containing the tricyclic macrolactone corePyran annulation: asymmetric synthesis of 2,6-disubstituted-4-methylene tetrahydropyransBioactive substances with anti-neoplastic efficacy from marine invertebrates: Bryozoa, Mollusca, Echinodermata and Urochordata.Neristatin 1 provides critical insight into bryostatin 1 structure-function relationshipsUtilizing the power of microbial genetics to bridge the gap between the promise and the application of marine natural products.PKC in Regenerative Therapy: New Insights for Old Targets.Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependentA multicentre phase II trial of bryostatin-1 in patients with advanced renal cancer.Challenges to the development of bryostatin-type anticancer drugs based on the activation mechanism of protein kinase Cδ.Protein kinase C pharmacology: refining the toolbox.Synthesis and biological activities of simplified analogs of the natural PKC ligands, bryostatin-1 and aplysiatoxin.Design, synthesis, and biological evaluation of diminutive forms of (+)-spongistatin 1: lessons learned.Concise synthesis of the bryostatin A-ring via consecutive C-C bond forming transfer hydrogenations.
P2860
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P2860
The rational design of potential chemotherapeutic agents: synthesis of bryostatin analogues.
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The rational design of potenti ...... hesis of bryostatin analogues.
@ast
The rational design of potenti ...... hesis of bryostatin analogues.
@en
type
label
The rational design of potenti ...... hesis of bryostatin analogues.
@ast
The rational design of potenti ...... hesis of bryostatin analogues.
@en
prefLabel
The rational design of potenti ...... hesis of bryostatin analogues.
@ast
The rational design of potenti ...... hesis of bryostatin analogues.
@en
P2093
P2860
P1476
The rational design of potenti ...... thesis of bryostatin analogues
@en
P2093
P2860
P304
P356
10.1002/(SICI)1098-1128(199909)19:5<388::AID-MED6>3.0.CO;2-H
P577
1999-09-01T00:00:00Z