Synthesis and biological activities of simplified analogs of the natural PKC ligands, bryostatin-1 and aplysiatoxin. - Wikidata - awgldk - TriplyDB

Synthesis and biological activities of simplified analogs of the natural PKC ligands, bryostatin-1 and aplysiatoxin.

Synthesis and biological activities of simplified analogs of the natural PKC ligands, bryostatin-1 and aplysiatoxin.

http://www.wikidata.org/entity/Q38200047

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Recent advances in isolation, synthesis, and evaluation of bioactivities of bispyrroloquinone alkaloids of marine origin Toward a biorelevant structure of protein kinase C bound modulators: design, synthesis, and evaluation of labeled bryostatin analogues for analysis with rotational echo double resonance NMR spectroscopy PKC in Regenerative Therapy: New Insights for Old Targets.Total synthesis and complete structural assignment of gambieric acid A, a large polycyclic ether marine natural product.Structural optimization of 10-methyl-aplog-1, a simplified analog of debromoaplysiatoxin, as an anticancer lead.Syntheses of C17-C27 fragments of 20-deoxybryostatins for assembly using Julia and metathesis reactions.Total synthesis of 7-des-O-pivaloyl-7-O-benzylbryostatin 10.Synthetic approaches to the C11-C27 fragments of bryostatins.The evolution of a stereoselective synthesis of the C1-C16 fragment of bryostatins.Molecular Targets of Active Anticancer Compounds Derived from Marine Sources.

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Synthesis and biological activities of simplified analogs of the natural PKC ligands, bryostatin-1 and aplysiatoxin.

http://www.wikidata.org/entity/Q38200047

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Synthesis and biological activ ...... bryostatin-1 and aplysiatoxin.

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Synthesis and biological activ ...... bryostatin-1 and aplysiatoxin.

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Synthesis and biological activ ...... bryostatin-1 and aplysiatoxin.

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The Chemical Record

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Synthesis and biological activ ...... bryostatin-1 and aplysiatoxin.

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Kazuhiro Irie

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Ryo C Yanagita

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Human munc13 is a diacylglycerol receptor that induces apoptosis and may contribute to renal cell injury in hyperglycemia

Total synthesis of bryostatin 7 via C-C bond-forming hydrogenation

Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability

Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence

Total synthesis of bryostatin 16 using atom-economical and chemoselective approaches

Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma

RasGRPs are targets of the anti-cancer agent ingenol-3-angelate

Natural products as sources of new drugs over the 30 years from 1981 to 2010

Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein.

Toward the identification of selective modulators of protein kinase C (PKC) isozymes: establishment of a binding assay for PKC isozymes using synthetic C1 peptide receptors and identification of the critical residues involved in the phorbol ester bi

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251-267

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scholarly article

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10.1002/TCR.201300036

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2

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14

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Ryo C. Yanagita

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2014-02-20T00:00:00Z

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24677503

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