Akt Cys-310-targeted inhibition by hydroxylated benzene derivatives is tightly linked to their immunosuppressive effects
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JS-III-49, a hydroquinone derivative, exerts anti-inflammatory activity by targeting Akt and p38.Regulatory effect of cinnamaldehyde on monocyte/macrophage-mediated inflammatory responses.Beauvericin, a cyclic peptide, inhibits inflammatory responses in macrophages by inhibiting the NF-κB pathway.NF-κB/AP-1-targeted inhibition of macrophage-mediated inflammatory responses by depigmenting compound AP736 derived from natural 1,3-diphenylpropane skeleton.21-O-angeloyltheasapogenol E3, a novel triterpenoid saponin from the seeds of tea plants, inhibits macrophage-mediated inflammatory responses in a NF-κB-dependent manner.Molecular mechanism of protopanaxadiol saponin fraction-mediated anti-inflammatory actions.p47phox and reactive oxygen species production modulate expression of microRNA-451 in macrophagesThe dietary flavonoid Kaempferol mediates anti-inflammatory responses via the Src, Syk, IRAK1, and IRAK4 molecular targets.A direct protein kinase B-targeted anti-inflammatory activity of cordycepin from artificially cultured fruit body of Cordyceps militaris.Syk/Src pathway-targeted inhibition of skin inflammatory responses by carnosic acidBAY 11-7082 is a broad-spectrum inhibitor with anti-inflammatory activity against multiple targets.4-Isopropyl-2,6-bis(1-phenylethyl)aniline 1, an Analogue of KTH-13 Isolated from Cordyceps bassiana, Inhibits the NF-κB-Mediated Inflammatory Response.Radical scavenging activity-based and AP-1-targeted anti-inflammatory effects of lutein in macrophage-like and skin keratinocytic cells.Ginsenoside Rp1, a Ginsenoside Derivative, Blocks Promoter Activation of iNOS and COX-2 Genes by Suppression of an IKKβ-mediated NF-кB Pathway in HEK293 Cells.Extracellular signal-regulated kinase is a direct target of the anti-inflammatory compound amentoflavone derived from Torreya nucifera.Glycosylation enables aesculin to activate Nrf2Therapeutic Effect of the Tuber of Alisma orientale on Lipopolysaccharide-Induced Acute Lung Injury.Anticancer effect of joboksansam, Korean wild ginseng germinated from bird fecesLancemaside A from Codonopsis lanceolata modulates the inflammatory responses mediated by monocytes and macrophages.ATP-Binding Pocket-Targeted Suppression of Src and Syk by Luteolin Contributes to Its Anti-Inflammatory Action.In vitro antioxidative and anti-inflammatory effects of the compound K-rich fraction BIOGF1K, prepared from Panax ginseng.p38 MAPK/PP2Acα/TTP pathway on the connection of TNF-α and caspases activation on hydroquinone-induced apoptosis.Hydroquinone-induced FOXP3-ADAM17-Lyn-Akt-p21 signaling axis promotes malignant progression of human leukemia U937 cells.Anti-inflammatory activity of AP-SF, a ginsenoside-enriched fraction, from Korean ginsengHydroquinone suppresses IFN-β expression by targeting AKT/IRF3 pathway.Hydroquinone Strongly Alleviates Focal Ischemic Brain Injury via Blockage of Blood-Brain Barrier Disruption in Rats.Src/Syk-Targeted Anti-Inflammatory Actions of Triterpenoidal Saponins from Gac (Momordica cochinchinensis) Seeds.Hydroquinone Exhibits In Vitro and In Vivo Anti-Cancer Activity in Cancer Cells and Mice.
P2860
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P2860
Akt Cys-310-targeted inhibition by hydroxylated benzene derivatives is tightly linked to their immunosuppressive effects
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Akt Cys-310-targeted inhibitio ...... heir immunosuppressive effects
@ast
Akt Cys-310-targeted inhibitio ...... heir immunosuppressive effects
@en
type
label
Akt Cys-310-targeted inhibitio ...... heir immunosuppressive effects
@ast
Akt Cys-310-targeted inhibitio ...... heir immunosuppressive effects
@en
prefLabel
Akt Cys-310-targeted inhibitio ...... heir immunosuppressive effects
@ast
Akt Cys-310-targeted inhibitio ...... heir immunosuppressive effects
@en
P2093
P2860
P356
P1476
Akt Cys-310-targeted inhibitio ...... heir immunosuppressive effects
@en
P2093
Byong Chul Yoo
Jae Youl Cho
Jaehwi Lee
Ji Yeon Lee
Joo Young Kim
Keum-Jin Yang
Moo-Ho Won
Sanghee Kim
Won-Jea Cho
P2860
P304
P356
10.1074/JBC.M109.074872
P407
P50
P577
2010-01-06T00:00:00Z