The methymycin/pikromycin pathway: a model for metabolic diversity in natural product biosynthesis
about
Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide HydrolaseGrassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation.CYP105-diverse structures, functions and roles in an intriguing family of enzymes in Streptomyces.Twelve-membered macrolactones: privileged scaffolds for the development of new therapeutics.Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides.Functional Characterization of a Dehydratase Domain from the Pikromycin Polyketide SynthaseSalinipyrone and Pacificanone Are Biosynthetic By-products of the Rosamicin Polyketide Synthase.Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin.Comparative analysis of the biosynthetic systems for fungal bicyclo[2.2.2]diazaoctane indole alkaloids: the (+)/(-)-notoamide, paraherquamide and malbrancheamide pathways.A conformational NMR analysis of methymycin aglycones: complete and unambiguous assignments of stereochemically diverse glycosylated methymycin analogs by 1D and 2D NMR techniques and molecular modeling.Identification of a Thioesterase Bottleneck in the Pikromycin Pathway through Full-Module Processing of Unnatural Pentaketides.Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins.
P2860
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P2860
The methymycin/pikromycin pathway: a model for metabolic diversity in natural product biosynthesis
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The methymycin/pikromycin path ...... n natural product biosynthesis
@ast
The methymycin/pikromycin path ...... n natural product biosynthesis
@en
type
label
The methymycin/pikromycin path ...... n natural product biosynthesis
@ast
The methymycin/pikromycin path ...... n natural product biosynthesis
@en
prefLabel
The methymycin/pikromycin path ...... n natural product biosynthesis
@ast
The methymycin/pikromycin path ...... n natural product biosynthesis
@en
P2860
P1476
The methymycin/pikromycin path ...... n natural product biosynthesis
@en
P2093
David H Sherman
Jeffrey D Kittendorf
P2860
P304
P356
10.1016/J.BMC.2008.10.082
P407
P577
2008-11-05T00:00:00Z