Successful treatment with posaconazole of a patient with chronic Chagas disease and systemic lupus erythematosus.
about
Management of trypanosomiasis and leishmaniasisVNI cures acute and chronic experimental Chagas diseaseImmunosuppression and Chagas disease: a management challengeAntitrypanosomal Lead Discovery: Identification of a Ligand-Efficient Inhibitor of Trypanosoma cruzi CYP51 and Parasite Growth4-Aminopyridyl-Based CYP51 Inhibitors as Anti- Trypanosoma cruzi Drug Leads with Improved Pharmacokinetic Profile and in Vivo PotencyActivity in vivo of anti-Trypanosoma cruzi compounds selected from a high throughput screeningDiverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51High throughput screening for anti-Trypanosoma cruzi drug discoveryUsing a non-image-based medium-throughput assay for screening compounds targeting N-myristoylation in intracellular Leishmania amastigotesUtilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas DiseaseDevelopment of a Fluorescence-based Trypanosoma cruzi CYP51 Inhibition Assay for Effective Compound Triaging in Drug Discovery Programmes for Chagas DiseaseSterol 14alpha-demethylase (CYP51) as a therapeutic target for human trypanosomiasis and leishmaniasisA nonazole CYP51 inhibitor cures Chagas' disease in a mouse model of acute infection.Methodological advances in drug discovery for Chagas disease.Current and developing therapeutic agents in the treatment of Chagas diseaseDrug strategies targeting CYP51 in neglected tropical diseasesWould selenium supplementation aid in therapy for Chagas disease?Successful treatment of Old World cutaneous leishmaniasis caused by Leishmania infantum with posaconazole.Genome profiling of sterol synthesis shows convergent evolution in parasites and guides chemotherapeutic attack.Non-bisphosphonate inhibitors of isoprenoid biosynthesis identified via computer-aided drug design.Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones.Chagas heart disease: report on recent developments.Biomarkers of therapeutic responses in chronic Chagas disease: state of the art and future perspectives.Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly Sensitive In Vivo Imaging.Emerging and under-recognized Chagas cardiomyopathy in non-endemic countriesAntiparasitic Effect of Vitamin B12 on Trypanosoma cruzi.Targeting Trypanosoma cruzi sterol 14α-demethylase (CYP51)Advances in Chagas disease drug development: 2009-2010In vitro and in vivo studies of the antiparasitic activity of sterol 14α-demethylase (CYP51) inhibitor VNI against drug-resistant strains of Trypanosoma cruzi.Cellular response to Trypanosoma cruzi infection induces secretion of defensin α-1, which damages the flagellum, neutralizes trypanosome motility, and inhibits infection.Design or screening of drugs for the treatment of Chagas disease: what shows the most promise?The use of steroids to prevent cutaneous reactions to benznidazole in patients with Chagas disease.Current status of Chagas disease chemotherapy.Guidelines on the treatment of chronic coinfection by Trypanosoma cruzi and HIV outside endemic areas.The emerging role of amiodarone and dronedarone in Chagas disease.Epidemiology of Chagas disease in Europe: many calculations, little knowledge.An approach to the management of Trypanosoma cruzi infection (Chagas' disease) in immunocompromised patients.Therapeutical approaches under investigation for treatment of Chagas disease.Chagas disease drug discovery: toward a new era.Recent clinical trials for the etiological treatment of chronic chagas disease: advances, challenges and perspectives.
P2860
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P2860
Successful treatment with posaconazole of a patient with chronic Chagas disease and systemic lupus erythematosus.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Successful treatment with posa ...... systemic lupus erythematosus.
@ast
Successful treatment with posa ...... systemic lupus erythematosus.
@en
type
label
Successful treatment with posa ...... systemic lupus erythematosus.
@ast
Successful treatment with posa ...... systemic lupus erythematosus.
@en
prefLabel
Successful treatment with posa ...... systemic lupus erythematosus.
@ast
Successful treatment with posa ...... systemic lupus erythematosus.
@en
P2093
P2860
P50
P1476
Successful treatment with posa ...... systemic lupus erythematosus.
@en
P2093
Julio A Urbina
María-Jesús Pinazo
Paulo Luis López-Chejade
P2860
P304
P356
10.4269/AJTMH.2010.09-0620
P407
P5008
P577
2010-04-01T00:00:00Z