about
Molecular traffic jams on DNARemodeling of the Rad51 DNA strand-exchange protein by the Srs2 helicase.Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis.Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiaeVisualizing protein movement on DNA at the single-molecule level using DNA curtainsSrs2 promotes synthesis-dependent strand annealing by disrupting DNA polymerase δ-extending D-loopsRad52 SUMOylation affects the efficiency of the DNA repair.Unwinding of synthetic replication and recombination substrates by Srs2.An S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control.Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functionsReconstitution of DNA repair synthesis in vitro and the role of polymerase and helicase activitiesMultiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1.Regulation of DNA pairing in homologous recombination.Functions of Fun30 chromatin remodeler in regulating cellular resistance to genotoxic stressRegulation of recombination at yeast nuclear pores controls repair and triplet repeat stability.Overcoming natural replication barriers: differential helicase requirements.Mechanism of DNA damage tolerance.Srs2 and Mus81-Mms4 Prevent Accumulation of Toxic Inter-Homolog Recombination Intermediates.Homologous recombination and its regulationDual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylationPro-recombination Role of Srs2 Protein Requires SUMO (Small Ubiquitin-like Modifier) but Is Independent of PCNA (Proliferating Cell Nuclear Antigen) Interaction.PARI overexpression promotes genomic instability and pancreatic tumorigenesis.The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis.Histone H2B mono-ubiquitylation maintains genomic integrity at stalled replication forks.Metabolism of postsynaptic recombination intermediates.Readers of PCNA modificationsA novel protein, Rsf1/Pxd1, is critical for the single-strand annealing pathway of double-strand break repair in Schizosaccharomyces pombe.Expansion of Interstitial Telomeric Sequences in Yeast.Depletion of Werner helicase results in mitotic hyperrecombination and pleiotropic homologous and nonhomologous recombination phenotypes.Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous Recombination Regulation.Dissociation of Rad51 Presynaptic Complexes and Heteroduplex DNA Joints by Tandem Assemblies of Srs2.Modulation of meiotic homologous recombination by DNA helicases.A change of view: homologous recombination at single-molecule resolution.RTEL1 inhibits trinucleotide repeat expansions and fragility.Def1 and Dst1 play distinct roles in repair of AP lesions in highly transcribed genomic regions.The Main Role of Srs2 in DNA Repair Depends on Its Helicase Activity, Rather than on Its Interactions with PCNA or Rad51
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Srs2: the "Odd-Job Man" in DNA repair.
@ast
Srs2: the "Odd-Job Man" in DNA repair.
@en
type
label
Srs2: the "Odd-Job Man" in DNA repair.
@ast
Srs2: the "Odd-Job Man" in DNA repair.
@en
prefLabel
Srs2: the "Odd-Job Man" in DNA repair.
@ast
Srs2: the "Odd-Job Man" in DNA repair.
@en
P2860
P921
P1433
P1476
Srs2: the "Odd-Job Man" in DNA repair.
@en
P2093
Victoria Marini
P2860
P304
P356
10.1016/J.DNAREP.2010.01.007
P50
P577
2010-01-21T00:00:00Z
2010-03-02T00:00:00Z